134022-45-0

Basic information

• Product Name: 4-methoxyphenyl 2-methylpropanoate
• Synonyms: 4-methoxyphenyl 2-methylpropanoate
• CAS NO: 134022-45-0
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• Mol File: 134022-45-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-methoxyphenyl 2-methylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxyphenyl 2-methylpropanoate(134022-45-0)
• EPA Substance Registry System: 4-methoxyphenyl 2-methylpropanoate(134022-45-0)

Safety Data

• Hazardous Substances Data: 134022-45-0(Hazardous Substances Data)

Upstream product

• 16883-61-7 trimethylsilyl isobutyrate 
• 6689-38-9 (4-methoxyphenoxy)trimethylsilane 
• 150-76-5 4-methoxy-phenol 
• 2040-20-2 4-methoxyisobutyrophenone 
• 121-97-1 4-Methoxypropiophenone 
• 255042-69-4 4-methoxyphenyl 2-bromo-2-methylpropanoate 
• 1612216-60-0 4-methoxyphenyl 2-iodo-2-methylpropanoate 
• 97-72-3 2-Methylpropionic anhydride 
• 201230-82-2 carbon monoxide 
• 73086-84-7 1-isopropyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt 

Relevant articles and documents

Radical Carbonylation under Low CO Pressure: Synthesis of Esters from Activated Alkylamines at Transition Metal-Free Conditions

High CO pressure (> 40 bar) is usually needed in radical carbonylation reactions in the absence of metal catalyst. In this communication, we developed a transition-metal-free radical carbonylation of activated alkylamines with phenols and alcohols under low CO pressure (1—6 bar). Various esters were obtained in moderate to excellent yields under simple reaction conditions with good functional group compatibility.

DMAP-based flexible polymer networks formed via Heck coupling as efficient heterogeneous organocatalysts

Two DMAP-based flexible polymer networks TPB-DMAP and TPA-DMAP have been successfully synthesized via palladium catalyzed Heck cross-coupling. The structures of these polymers were confirmed by solid state 13C CP/MAS and Fourier transform infrared spectroscopy (FTIR). Although both polymers have negligible surface areas, they exhibit excellent catalytic efficiency for the acylation of 1-phenylethanol with acetic anhydride due to their good swelling capacities. Utilized as a typical catalyst, the polymer TPA-DMAP shows high activities for acylation of a variety of alcohols to the corresponding esters. Moreover, the catalyst can be recycled at least ten times without obvious loss of catalytic activity.

Rhodium-catalyzed ketone methylation using methanol under mild conditions: Formation of α-branched products

The rhodium-catalyzed methylation of ketones has been accomplished using methanol as the methylating agent and the hydrogen-borrowing method. The sequence is notable for the relatively low temperatures that are required and for the ability of the reaction system to form α-branched products with ease. Doubly alkylated ketones can be prepared from methyl ketones and two different alcohols by using a sequential one-pot iridium- and rhodium-catalyzed process. Uniquely effective for making branched alkyl products from ketones (see scheme): The scope of the presented reaction includes aromatic and aliphatic ketones and consecutive one-pot double alkylation reactions to provide a convenient route to branched ketones from simple methyl ketones. A brief study into the mechanism of the reaction has given evidence for an aldol-based reaction pathway.