134029-84-8Relevant articles and documents
Synthesis of dimethoxy activated benzimidazoles and bisbenzimidazoles
Alamgir, Mahiuddin,Black, David St C.,Bowyer, Paul K.,Condie, Glenn C.,Kumar, Naresh,Martinovic, Vesna,Sholihin, Hayat,Wood, Joanne
, p. 1189 - 1217 (2020/09/18)
A range of 2-substituted-4,6-dimethoxy activated benzimidazoles and 2,2'-bisbenzimidazoles have been synthesized from 2-aminoanilide derivatives under acidic conditions. The starting materials were prepared either by acylation from 3,5-dimethoxyaniline followed by nitration, or by acylation from 3,5-dimethoxy-2-nitroaniline. The 2-nitroanilides were then reduced by palladium catalyzed reaction with hydrazine and subsequent acid catalyzed cyclization giving the corresponding 4,6-dimethoxybenzimidazoles and 4,6-dimethoxy-2,2'-bisbenzimidazoles. In addition, 2-phenyl-4,5,6-trimethoxybenzimidazole has been synthesized using a similar procedure.
Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties
Bertini, Simone,Calderone, Vincenzo,Carboni, Isabella,Maffei, Roberta,Martelli, Alma,Martinelli, Adriano,Minutolo, Filippo,Rajabi, Mehdi,Testai, Lara,Tuccinardi, Tiziano,Ghidoni, Riccardo,MacChia, Marco
experimental part, p. 6715 - 6724 (2010/10/19)
New resveratrol (RES) analogs were developed by replacing the aromatic 'core' of our initial naphthalene-based RES analogs with pseudo-heterocyclic (salicylaldoxime) or heterocyclic (benzofuran, quinoline, and benzothiazole) scaffolds. The resulting analo
A convenient method for the synthesis of 3,5,7-trimethoxy-2-phenyl-4-quinolones
Beney,Hadjeri,Mariotte,Boumendjel
, p. 7037 - 7039 (2007/10/03)
The synthesis of 2-aryl-3,5,7-trimethoxy-4-quinolones was accomplished in three steps starting from 3,5-dimethoxyaniline and an aroyl chloride. These structures might be used as potential flavonol analogs. (C) 2000 Elsevier Science Ltd.