1341128-21-9Relevant articles and documents
Synthesis of aryl-substituted naphthalenes by chemoselective Suzuki-Miyaura reactions of bromo-trifluoromethanesulfonyloxy-naphthalenes. Influence of steric and electronic parameters
Hassan, Zahid,Hussain, Munawar,Villinger, Alexander,Langer, Peter
, p. 6305 - 6313 (2012/08/27)
Chemoselective Suzuki-Miyaura reactions of 2-bromo-1- (trifluoromethanesulfonyloxy)naphthalene, 1-bromo-2- (trifluoromethanesulfonyloxy) naphthalene and 2-acetyl-4-bromo-1- (trifluoromethanesulfonyloxy)naphthalene, which are all readily available from the corresponding tetralone derivatives, afforded a variety of mono- and diarylnaphthalenes. The reactions generally proceed with excellent chemoselectivity in favour of the bromide position, no matter whether the bromide is located at position 1 or 2 of the naphthalene or whether the carbon attached to the triflate group is electronically more deficient by the presence of a neighbouring acetyl group.