134180-62-4

Basic information

• Product Name: (S)-(+)-2-Phenyl-3-oxa-5-hexensaeure-ethylester
• Synonyms: (S)-(+)-2-Phenyl-3-oxa-5-hexensaeure-ethylester
• CAS NO: 134180-62-4
• Molecular Weight: 220.268
• Mol File: 134180-62-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-(+)-2-Phenyl-3-oxa-5-hexensaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-Phenyl-3-oxa-5-hexensaeure-ethylester(134180-62-4)
• EPA Substance Registry System: (S)-(+)-2-Phenyl-3-oxa-5-hexensaeure-ethylester(134180-62-4)

Safety Data

• Hazardous Substances Data: 134180-62-4(Hazardous Substances Data)

Upstream product

• 51479-73-3 allyl trichloroacetimidate 
• 13704-09-1 (S)-(-)-ethyl mandelate 
• 106-95-6 allyl bromide 

Downstream Products

• 134180-73-7 (1'S,2S,3R,4R)-3-<(4-tert-Butylphenyl)amino>-4-<(camphanoyloxy)methyl>tetrahydro-2-phenylfuran 
• 134180-59-9 (1R,5S,8S)-2-(4-tert-Butylphenyl)-8-phenyl-3,7-dioxa-2-azabicyclo<3.3,0>octan 
• 134180-69-1 (2S,3R,4R)-3-<(4-tert-Butylphenyl)amino>tetrahydro-4-(hydroxymethyl)-2-phenylfuran 
• 701245-62-7 allyloxy-phenyl-acetic acid N'-phenyl-hydrazide 
• 134180-64-6 (S)-2-Phenyl-3-oxa-5-hexanal 

Relevant articles and documents

One-Pot Generation and Conversion of Trichloroacetimidates for the Racemization-Free Allylation and Benzylation of α-Hydroxyesters and the Enantiopure Synthesis of a Chiral Diglycole

Ο-Allylations and Ο-benzylations of α-hydroxy esters (3a-3c) are performed without racemization. The reagents applied, Ο-allyl- and Ο-benzyltrichloroacetimidate (5a, 5b) are prepared and converted in a one-pot-procedure. After protection by benzylation (S)-(-)-ethyl lactate (3a) is converted by a sequence of carbonyl reduction, alcohol activation, ether formation, and deprotection to the optically active diglycole derivative 1a.

Enantiomerically Pure 3,7-Dioxa-2-azabicyclooctanes by Intramolecular 1,3-Dipolar Cycloaddition of Nitrones

Starting with chiral non-racemic esters of lactic acid 7 and mandelic 8, respectively, chiral nitrones 4 have been prepared.They spontaneously undergo an intramolecular cycloaddition which proceeds with asymmetric induction by the chiral center yielding e