1342304-79-3Relevant articles and documents
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds
Zhao, Huaping,Liu, Yuxiu,Cui, Zhipeng,Beattie, David,Gu, Yucheng,Wang, Qingmin
, p. 11711 - 11717 (2012/04/17)
Heterocyclic rings were introduced into the core structure of s-triazine to design and synthesize a series of novel triazines containing arylmethylamino moieties. These compounds were characterized by using spectroscopic methods and elemental analysis. Their herbicidal, insecticidal, fungicidal, and antitumor activities were evaluated. Most of these compounds exhibited good herbicidal activity, especially against the dicotyledonous weeds, and compound F8 was almost at the same level as the control compound atrazine. Their structure-activity relationships were discussed. At the same time, some triazines had interesting fungicidal and insecticidal activities, of which F4 exhibited 100% efficacy against Puccinia triticina even at 20 ppm, and F5 showed Lepidopteran-specific activity in both leaf-piece and artificial diet assays. Moreover, these compounds showed antitumor activities against leukemia HL-60 cell line and lung adenocarcinoma A-549 cell line.
