134340-00-4 Usage
Description
HEPTAMETHYLDISILAZANE, also known as Methanamine, 1,1-Bis(trimethylsilyl), is a colorless liquid with a boiling point of 70°C at 25 mm Hg. Its hydrochloride salt has a melting point of 191°C. It is a reagent used in the preparation of N-bis(trimethylsilyl)methyl amines, imines, and serves as a synthetic equivalent of N-methyl, N-(trimethylsilyl)methyl carbanion and [N-CH] dianion synthons. Additionally, it acts as an N-protecting group in various chemical reactions.
Uses
Used in Chemical Synthesis:
HEPTAMETHYLDISILAZANE is used as a reagent for the preparation of N-bis(trimethylsilyl)methyl amines and imines, which are important intermediates in the synthesis of various organic compounds.
Used as a Synthetic Equivalent:
HEPTAMETHYLDISILAZANE serves as a synthetic equivalent of N-methyl, N-(trimethylsilyl)methyl carbanion and [N-CH] dianion synthons, which are useful in the synthesis of complex organic molecules.
Used as an N-Protecting Group:
HEPTAMETHYLDISILAZANE is used as an N-protecting group in chemical reactions, which helps to prevent unwanted side reactions and improve the yield of the desired product.
Preparation
It is prepared by lithium metal mediated
reductive silylation of trimethylsilyl cyanide.
Check Digit Verification of cas no
The CAS Registry Mumber 134340-00-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,3,4 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134340-00:
(8*1)+(7*3)+(6*4)+(5*3)+(4*4)+(3*0)+(2*0)+(1*0)=84
84 % 10 = 4
So 134340-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H21NSi2/c1-9(2,3)7(8)10(4,5)6/h7H,8H2,1-6H3
