13437-75-7

Basic information

• Product Name: 1-Phenyl-2-(thiobenzoyl)hydrazine
• Synonyms: 1-Phenyl-2-(thiobenzoyl)hydrazine;N'-(Phenyl)thiobenzoic acid hydrazide
• CAS NO: 13437-75-7
• Molecular Formula: C₁₃H₁₂N₂S
• Molecular Weight: 228.31
• Mol File: 13437-75-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 92 °C
• Boiling Point: 348.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.234±0.06 g/cm3(Predicted)
• PKA: 6.57±0.70(Predicted)
• CAS DataBase Reference: 1-Phenyl-2-(thiobenzoyl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-2-(thiobenzoyl)hydrazine(13437-75-7)
• EPA Substance Registry System: 1-Phenyl-2-(thiobenzoyl)hydrazine(13437-75-7)

Safety Data

• Hazardous Substances Data: 13437-75-7(Hazardous Substances Data)

Usage

Class

Organic compound

Explanation

1-Phenyl-2-(thiobenzoyl)hydrazine is an organic compound as it is primarily composed of carbon, hydrogen, and nitrogen atoms.

Explanation

The chemical formula represents the composition of the compound, with 13 carbon atoms, 12 hydrogen atoms, 2 nitrogen atoms, 1 oxygen atom, and 1 sulfur atom.

Explanation

The compound consists of a phenyl group (a ring with a side chain) attached to one nitrogen atom of a hydrazine group (NH-NH2), and a thiobenzoyl group (a thioester with a benzene ring) attached to the other nitrogen atom.

Explanation

1-Phenyl-2-(thiobenzoyl)hydrazine is commonly used as a building block in organic synthesis for the preparation of various derivatives.

Explanation

The compound has the potential to act as an intermediate in the synthesis of pharmaceuticals and agrochemicals, which can be used in the development of drugs and pesticides.

Explanation

1-Phenyl-2-(thiobenzoyl)hydrazine has been studied for its potential biological activities, including its ability to inhibit the growth of fungi and bacteria.

Structure

Phenyl group and thiobenzoyl group attached to hydrazine

Usage

Building block in organic synthesis

Potential applications

Intermediate in pharmaceuticals and agrochemicals

Biological activities

Antifungal and antibacterial properties

Upstream product

• 936-61-8 Thiobenzoic acid O-ethyl ester 
• 60-29-7 diethyl ether 
• 100-63-0 phenylhydrazine 
• 121-68-6 dithiobenzoic acid 
• 942-91-6 Carboxymethyl dithiobenzoate 
• 19172-47-5 Lawessons reagent 
• 532-96-7 N-benzoyl-N'-phenylhydrazine 
• 40219-06-5 benzylidenecyanothioacetamide 
• 97651-32-6 p-tolylmethylenecyanothioacetamide 
• 39145-33-0 2-cyano-3-(4-chlorophenyl)-prop-2-enethioamide 
• 15424-14-3 N-phenylbenzohydrazonoyl chloride 
• 98-07-7 Benzotrichlorid 

Downstream Products

• 14478-92-3 N-acetyl-N-phenyl-N'-thiobenzoylphenylhydrazine 
• 36358-07-3 2,4-Diphenyl-1,3,4-thiadiazolin 
• 52190-65-5 bis[α-(phenylhydrazono)phenyl]disulfide 
• 35222-88-9 3,5-diphenyl-[1,3,4]thiadiazole; chloride 
• 34241-53-7 3,3',5,5'-tetraphenyl-2(3H),2'(3'H)-spirobi-1,3,4-thiadiazole 
• 35288-76-7 1,3,5,7-tetraphenyl-1,5-dihydro-[1,3,4]thiadiazino[6,5-e][1,3,4]thiadiazine 
• 36358-10-8 2,2,3,5-tetraphenyl-2,3-dihydro-[1,3,4]thiadiazole 
• 63810-94-6 2,4-Diphenyl-4H-1,3,4-pyrido<3,2-e>thiadiazine 

Relevant articles and documents

Reactions with Hydrazonoyl Halides. Part 10. Formation of Thiohydrazide, Hydrazonoyl Sulfide and Arylazothiazole Derivatives

Hydrazonoyl halides react with α-thiocarbamoylcinnamonitrile derivatives, under alkaline conditions, to afford thiohydrazide (4), hydrazonoyl sulfide (7a,b) or arylazothiazole derivatives (9a,b), depending on the nature of the hydrazonoyl halide; a sequence leading to the formation of these products is discussed.

Studies on Organophosphorus Compounds. XXXIV. Syntheses of 2,3-Dihydro-1,3,4,2-Thiadiazaphospholes and Thiohydrazides

N'-Substituted hydrazides, 2, react with 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide, 1, in refluxing benzene to give 2,3-dihydro-1,3,4,2-thiadizaphospholes, 3; in one case also the thiohydrazide, 4e, was isolated.Benzohydrazide, 10