134511-41-4Relevant articles and documents
Process and intermediate for the preparation of 2-hydroxy-3-sulfido-3-phenyl propanoic acids
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, (2008/06/13)
STR1 This invention relates to intermediate compounds of formula (VI), wherein: R1 is (L)a --(CH2)b --(T)c --B; a is 0 or 1; b is 3 to 14; c is 0 or 1; L and T are independently sulfur, oxygen, CH=CH, C C, or CH2 ; B is H, C1-4 alkyl, ethynyl, trifluoromethyl, isopropenyl, furanyl, thienyl, cyclohexyl or phenyl unsubstituted or monosubstituted by Br, Cl, CF3, C1-4 alkoxy, C1-4 alkyl, methylthio or trifluoromethylthio; R2 and A are independently selected from H, CF3, C1-4 alkyl, C1-4 alkoxy, F, Cl, Br, I, OH, NO2 or NH2 ; or, when R1 and A are H, R2 is (L)a --(CH2)b --(T)c --B wherein a, b, c, L, T and B are as defined above; and M is H, Li, Na, K, NH4 or an organic ammonium cation, and their use in a process for preparing leukotriene antagonists.
A practical, enantioselective synthesis of SK and F 104353
Flisak,Gombatz,Holmes,Jarmas,Lantos,Mendelson,Novack,Remich,Snyder
, p. 6247 - 6254 (2007/10/02)
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