134516-40-8Relevant articles and documents
Heterocycle-Heterocycle Strategy for 4,5-Disubstituted Pyrrolidine 2,3-Diones: Reductive Rearrangement Approach from Isoxazole Esters
Kamath, Prashantha,Jadhav, Vaibhav,Lal, Mukul
, p. 1146 - 1150 (2021)
The work demonstrates the heterocycle-heterocycle interconversion strategy to access 4,5-disubstituted 3-hydroxy-2-pyrrolidinone in moderate to good yields (50-80%). The approach has a distinct advantage over a multicomponent reaction approach as it allow