134557-74-7

Basic information

• Product Name: Carbamic acid, [(1S)-1-(azidomethyl)-2-phenylethyl]-, 1,1-dimethylethyl ester
• CAS NO: 134557-74-7
• Molecular Formula: C14H20N4O2
• Molecular Weight: 276.338
• Mol File: 134557-74-7.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-1-(azidomethyl)-2-phenylethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-1-(azidomethyl)-2-phenylethyl]-, 1,1-dimethylethyl ester(134557-74-7)
• EPA Substance Registry System: Carbamic acid, [(1S)-1-(azidomethyl)-2-phenylethyl]-, 1,1-dimethylethyl ester(134557-74-7)

Safety Data

• Hazardous Substances Data: 134557-74-7(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 154669-56-4 (2S)-2-[N-(tert-butoxycarbonyl)amino]-1-iodo-3-phenylpropane 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 63-91-2 L-phenylalanine 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 4522-04-7 ethyl N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-phenylalaninate 
• 3182-95-4 L-Phenylalaninol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 87694-53-9 Boc-Phe-OH N,O-dimethyl hydroxamate 
• 141403-49-8 (2S)-2-[N-(tert-butoxycarbonyl)amino]-3-phenyl-O-(4-methylphenylsulfonyl)propan-1-ol 
• 185384-15-0 (S)-tert-butyl (1-bromo-3-phenylpropan-2-yl)carbamate 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 126301-19-7 (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate 

Downstream Products

• 1643565-22-3 (S)-tert-butyl 2-benzyl-5-methyl-3,4-dihydropyrazine-1(2H)-carboxylate 
• 1643565-17-6 (S)-tert-butyl allyl(1-azido-3-phenylpropan-2-yl)carbamate 
• 1172597-05-5 tert-butyl (S)-3-phenyl-1-(3-((S)-1-phenylethyl)thioureido)propan-2-ylcarbamate 
• 1172597-04-4 tert-butyl (S)-3-phenyl-1-(3-((R)-1-phenylethyl)thioureido)propan-2-ylcarbamate 
• 1350897-02-7 1-[(2S)-1-azido-3-phenylpropan-2-yl]-3-[3,5-bis(trifluoromethyl)phenyl]thiourea 

Relevant articles and documents

Development of Chiral Organosuperbase Catalysts Consisting of Two Different Organobase Functionalities

In the field of chiral Br?nsted base catalysis, a new generation of chiral catalysts has been highly anticipated to overcome the intrinsic limitation of pronucleophiles that are applicable to the enantioselective reactions. Herein, we reveal conceptually new chiral Br?nsted base catalysts consisting of two different organobase functionalities, one of which functions as an organosuperbase and the other as the substrate recognition site. Their prominent activity, which stems from the distinctive cooperative function by the two organobases in a single catalyst molecule, was demonstrated in the unprecedented enantioselective direct Mannich-type reaction of α-phenylthioacetate as a less acidic pronucleophile. The present achievement would provide a new guiding principle for the design and development of chiral Br?nsted base catalysts and significantly broaden the utility of Br?nsted base catalysis in asymmetric organic synthesis.

[3 + 3] Cycloaddition of azides with in situ formed azaoxyallyl cations to synthesize 1,2,3,4-Tetrazines

A formal [3 + 3] cycloaddition reaction between azides and in situ formed azaoxyallyl cations has been realized. This reaction provided an efficient and practical pathway to synthesize 1,2,3,4-tetrazines in good yields under mild conditions. Biologically active molecules could also be well compatible, highlighting the potential value of this reaction.

N a aminopeptidase inhibitor and its preparation method and application

The invention discloses an aminopeptidase N inhibitor which has a chemical name of 2-((S)-3-(3-((S)-2-amino-3-phenylpropyl)urea)-2,6-dioxopiperidine-1-yl)-N-hydroxyacetamide hydrochloride and is a compound with a structural formula (I) described in the sp