1345691-39-5

Basic information

• Product Name: C₂₁H₁₂ClFN₄
• CAS NO: 1345691-39-5
• Molecular Weight: 374.804
• Mol File: 1345691-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₂ClFN₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₂ClFN₄(1345691-39-5)
• EPA Substance Registry System: C₂₁H₁₂ClFN₄(1345691-39-5)

Safety Data

• Hazardous Substances Data: 1345691-39-5(Hazardous Substances Data)

Upstream product

• 60467-61-0 2-amino-3-(4-fluorophenyl)-1,8-naphthyridine 
• 459-22-3 4-fluorophenylacetonitrile 
• 1082429-86-4 2-chloro-3-(4-fluorophenyl)-1,8-naphthyridine 
• 1082429-76-2 1,2-dihydro-3-(4-fluorophenyl)-1,8-naphthyridin-2-one 
• 1345691-31-7 C₂₁H₁₄ClFN₄ 
• 1153668-78-0 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine 
• 89-98-5 2-chloro-benzaldehyde 
• 7521-41-7 2-Aminonicotinaldehyde 

Relevant articles and documents

Green synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using PhI(OAc)2-Al2O3 under microwave irradiation

Alumina-supported iodobenzene diacetate [PhI(OAc)2-Al 2O3] is a highly efficient reagent for the oxidative cyclization of N-arylidene-N′-[3-(4-fluorophenyl)-[1,8]naphthyridin-2-yl]- hy-drazines 7 to 1-aryl-4-[4-fluoro phenyl]-1,2,4-triazolo[4,3-a][1,8] naphthyridines 8 in solvent-free conditions under microwave irradiation. The products are obtained in good yields and excellent purities. The structural assignments of compounds 3-8 were based on their spectral (IR, 1H NMR and MS) and analytical data.