13458-33-8 Usage
Description
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE is a chemical compound with the molecular formula C6H6N2S. It is a thiazole derivative with a nitrile functional group attached to the thiazole ring. This unique structure and reactivity make it a valuable component in the production of a variety of important chemical products.
Used in Pharmaceutical Industry:
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs.
Used in Agrochemical Industry:
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE is used as an intermediate in the synthesis of agrochemicals to help create effective products for agricultural applications.
Used in Organic Synthesis:
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE is used as a building block in organic synthesis to create more complex molecules, expanding its utility in various chemical reactions.
Used in Dye and Pigment Industry:
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE is used in the development of dyes and pigments, contributing to the creation of a wide range of colorants for different applications.
Used in Specialty Chemicals Production:
(2-METHYL-1,3-THIAZOL-4-YL)ACETONITRILE has applications in the development of specialty chemicals, where its unique properties can be leveraged for specific industrial needs.
Check Digit Verification of cas no
The CAS Registry Mumber 13458-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,5 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13458-33:
(7*1)+(6*3)+(5*4)+(4*5)+(3*8)+(2*3)+(1*3)=98
98 % 10 = 8
So 13458-33-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2S/c1-5-8-6(2-3-7)4-9-5/h4H,2H2,1H3
13458-33-8Relevant articles and documents
Design, synthesis, and biological testing of potential heme-coordinating nitric oxide synthase inhibitors
Litzinger, Elizabeth A.,Martasek, Pavel,Roman, Linda J.,Silverman, Richard B.
, p. 3185 - 3198 (2007/10/03)
Based on computer modeling of the active site of nitric oxide synthases (NOS), a series of 10 amidine compounds (9-18) was designed including potential inhibitors that involve the coordination of side-chain functional groups with the iron of the heme cofactor. The most potent and selective compound was the methylthio amidine analogue 9, which was more potent than l-nitroarginine with 185-fold selectivity for inhibition of neuronal NOS over endothelial NOS. It also exhibited time-dependent inhibition, but did not involve the mechanism previously proposed for other amidine inhibitors of NOS. None of the compounds, however, exhibited heme-binding characteristics according to absorption spectroscopy.
