1345824-05-6

Basic information

• Product Name: dimethyl 2,2'-((2-iodo-5-1,3-phenylene)bis(oxy))diacetate
• Synonyms: dimethyl 2,2'-((2-iodo-5-1,3-phenylene)bis(oxy))diacetate
• CAS NO: 1345824-05-6
• Molecular Weight: 380.136
• Mol File: 1345824-05-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 2,2'-((2-iodo-5-1,3-phenylene)bis(oxy))diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2,2'-((2-iodo-5-1,3-phenylene)bis(oxy))diacetate(1345824-05-6)
• EPA Substance Registry System: dimethyl 2,2'-((2-iodo-5-1,3-phenylene)bis(oxy))diacetate(1345824-05-6)

Safety Data

• Hazardous Substances Data: 1345824-05-6(Hazardous Substances Data)

Upstream product

• 108-46-3 recorcinol 
• 41046-67-7 2-iodoresorcinol 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 1345824-00-1 C₁₆H₁₉IO₁₀ 

Relevant articles and documents

A Chiral Pentafluorinated Isopropyl Group via Iodine(I)/(III) Catalysis

An I(I)/(III) catalysis strategy to construct an enantioenriched fluorinated isostere of the iPr group is reported. The difluorination of readily accessible α-CF3-styrenes is enabled by the in situ generation of a chiral ArIF2 species to forge a stereocentre with the substituents F, CH2F and CF3 (up to 95 %, >20:1 vicinal:geminal difluorination). The replacement of the metabolically labile benzylic proton results in a highly preorganised scaffold as was determined by X-ray crystallography (π→σ* and stereoelectronic gauche σ→σ* interactions). A process of catalyst editing is disclosed in which preliminary validation of enantioselectivity is placed on a structural foundation.