1345879-82-4Relevant articles and documents
Asymmetric synthesis of linezolid thiazolidine-2-thione derivatives via CS2 mediated decarboxylation cyclization
Bai, Meng-Meng,Cai, Jianfeng,Cui, De-Yun,Kong, Hong-Tao,Qu, Ying-Long,Shen, Bo-Yuan,Yan, Da-chao,Yang, Yi,Zhang, En,Zhang, Xiu-Juan
supporting information, (2020/04/08)
A mild and cost-effective decarboxylation cyclization method was developed for the synthesis of chiral 5-substituted thiazolidine-2-thione derivatives from β-amino oxazolidinones. This reaction was mediated by CS2 and allowed a highly stereoselective synthesis of linezolid thiazolidine-2-thione derivatives. The chirality of the linezolid base was completely retained in the final product.
PROCESSES FOR PREPARING LINEZOLID
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, (2011/11/13)
Processes and intermediates for preparing linezolid, and pharmaceutically acceptable salts thereof, are described herein.
