134612-80-9 Usage
Description
3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE is an organic compound characterized by its chemical structure, which includes a benzyl group with a nitro and hydroxyl functional group at the 5th and 4th positions, respectively, and a methoxy group at the 3rd position. It is a yellow solid, indicating its potential stability and visibility in various applications.
Uses
Used in Pharmaceutical Industry:
3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Research:
In the field of chemical research, 3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE serves as a valuable compound for studying the properties and reactivity of various functional groups. Its presence in chemical reactions can provide insights into the mechanisms and outcomes of these processes, contributing to the advancement of chemical knowledge.
Used in Dye and Pigment Industry:
3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE, due to its yellow solid appearance, can be utilized as a starting material for the production of dyes and pigments. Its chemical properties may allow for the creation of new colorants with specific characteristics, such as improved stability or solubility, for use in various industries.
Used in Material Science:
The unique structure of 3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE may also find applications in material science, where it could be used to develop new materials with specific properties. These materials could have potential uses in various industries, such as electronics, aerospace, or automotive, depending on their characteristics.
Preparation
Preparation by nitration of 4-hydroxy-3- methoxy-4′-methylbenzophenone with 65% nitric acid in acetic acid at 20°.
Check Digit Verification of cas no
The CAS Registry Mumber 134612-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,6,1 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134612-80:
(8*1)+(7*3)+(6*4)+(5*6)+(4*1)+(3*2)+(2*8)+(1*0)=109
109 % 10 = 9
So 134612-80-9 is a valid CAS Registry Number.
134612-80-9Relevant articles and documents
Convenient synthesis of tolcapone, a selective catechol-O-methyltransferase inhibitor
Manikumar, Govindarajan,Jin, Chunyang,Rehder, Kenneth S.
, p. 810 - 815 (2008/09/16)
A convenient and efficient synthesis of tolcapone from commercial 4-benzyloxy-3-methoxybenzaldehyde is presented. Grignard reaction of 4-benzyloxy-3-methoxybenzaldehyde (1) with p-tolylmagnesium bromide followed by Oppenauer oxidation of the hydroxyl func
Catechol derivatives
-
, (2008/06/13)
Catechol derivatives of the formula STR1 wherein Ra, Rb and Rc have the significance given herein, the ester and ether derivatives thereof which are hydrolyzable under physiological conditions and the pharmaceutically acceptable salts thereof are described and possess valuable pharmacological properties. In particular, they inhibit the enzyme catechol-O-methyltransferase (COMT), a soluble, magnesium-dependent enzyme which catalyses the transference of the methyl group of S-adensoylmethionine to a catechol substrate, whereby the corresponding methyl ethers are formed. Suitable substrates which can be O-methylated by COMT and which can thus be deactivated are, for example, extraneuornal catecholamines and exogeneously-administered therapeutically active substances having a catechol structure. Formula Ia above embraces not only compounds which form part of the invention, but also known compounds; the compounds which form part of the invention can be prepared according to known methods.
