134627-69-3

Basic information

• Product Name: 1-((4-(N,N-Dimethylamino)phenyl)methyl)-2-naphthol
• Synonyms: 1-((4-(N,N-Dimethylamino)phenyl)methyl)-2-naphthol
• CAS NO: 134627-69-3
• Molecular Weight: 277.366
• Mol File: 134627-69-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-((4-(N,N-Dimethylamino)phenyl)methyl)-2-naphthol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((4-(N,N-Dimethylamino)phenyl)methyl)-2-naphthol(134627-69-3)
• EPA Substance Registry System: 1-((4-(N,N-Dimethylamino)phenyl)methyl)-2-naphthol(134627-69-3)

Safety Data

• Hazardous Substances Data: 134627-69-3(Hazardous Substances Data)

Upstream product

• 135-19-3 β-naphthol 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 29546-14-3 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline 
• 859790-92-4 bis-(4-dimethylamino-benzyl)-sulfone 
• 1703-46-4 N,N-dimethyl-4-hydroxymethylaniline 
• 50-00-0 formaldehyd 
• 121-69-7 N,N-dimethyl-aniline 
• 132980-40-6 1-<(1H-Benzotriazol-1-yl)<4-(dimethylamino)phenyl>methyl>-2-naphthol 

Relevant articles and documents

Magnesium sulfate promoted efficient and green synthesis of aminoalkyl, amidoalkyl and diarylmethane derivatives

Under solvent-free condition, magnesium sulfate promoted the synthesis of substituted aminoalkyl naphthols, amidoalkyl naphthols and diarylmethane derivatives in excellent yield. Robust dehydrating nature and mild Lewis acidity of magnesium sulfate was exploited to carry out all the transformations.

o-(α-Benzotriazolylalkyl)phenols: Versatile Intermediates for the Synthesis of Substituted Phenols

Phenols and naphthols are benzotriazolylmethylated by 1-(hydroxymethyl)-1H-benzotriazole (13) (a formaldehyde derivative) in the o- or (if both o-positions are occupied) in the p-position.The reaction can be extended to other aldehydes in the case of the naphthols.The methylene group in the o-(benzotriazolylmethyl)phenols can be lithiated (but only after trimethylsilyl protection of the hydroxy group) and then substituted by various electrophiles.The benzotriazole residues in both the primary products and in their substituted derivatives can be displaced by the alkylanions of Grignard reagents or by hydride ions allowing the elaboration of many new types of substituted phenols. Key Words: Lithiation/ Mannich reaction/ Alkylation/ Grignard reaction/ Condensation