13466-98-3

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]-
• CAS NO: 13466-98-3
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Mol File: 13466-98-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]-(13466-98-3)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]-(13466-98-3)

Safety Data

• Hazardous Substances Data: 13466-98-3(Hazardous Substances Data)

Usage

General Description

The chemical "1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]-" is a compound with a molecular formula C16H14N2O2. It is a derivative of isoindole-1,3-dione, and it contains a 2-[(methylphenylamino)methyl]- group. 1H-Isoindole-1,3(2H)-dione, 2-[(methylphenylamino)methyl]- is a synthetic organic molecule that may have potential applications in the field of medicine, chemistry, or material science. Its specific properties and uses would depend on its reactivity, stability, and interactions with other chemicals, and may require further research and testing to fully understand.

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 1074-82-4 potassium phtalimide 
• 86451-26-5 2,2'-(phenyl-λ³-iodanediyl)bis(isoindoline-1,3-dione) 
• 136918-14-4 phthalimide 
• 50-00-0 formaldehyd 
• 100-61-8 N-methylaniline 

Relevant articles and documents

Synthesis and Structure of Hypervalent Iodine(III) Reagents Containing Phthalimidate and Application to Oxidative Amination Reactions

A new class of hypervalent iodine reagents containing phthalimidate was synthesized, and structurally characterized by X-ray analysis. The benziodoxole-based reagent displays satisfactory solubility in common organic solvents and is reasonably stable in solution as well as in the solid state. The reagent was used for the oxidative amination of the C(sp3)-H bond of N,N-dimethylanilines. In addition, the reagent was also applicable to oxidative amination with rearrangement of trialkylamines as well as enamines that were prepared in situ from secondary amines and aldehydes.

KI-catalyzed imidation of sp3 C-H bond adjacent to amide nitrogen atom

We have developed a new KI-catalyzed method for the imidation of an sp 3 C-H bond adjacent to an amide nitrogen atom by using TBHP (tert-butyl hydroperoxide, 70% aqueous solution) as the oxidant. This novel procedure tolerated air and moisture and provided a series of novel products in moderate to excellent yields under mild conditions.