134790-40-2 Usage
Description
4-Amino-1-3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone is a chemical compound that serves as an intermediate in the synthesis of Gemcitabine, a potent antitumor drug. It is characterized by its unique molecular structure, which includes a pyrimidine ring and a modified pentofuranosyl sugar moiety. 4-Amino-1-3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone plays a crucial role in the development of cancer treatments due to its ability to be converted into the active pharmaceutical ingredient, Gemcitabine.
Uses
Used in Pharmaceutical Industry:
4-Amino-1-3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone is used as an intermediate in the synthesis of Gemcitabine for its antitumor properties. It is specifically utilized in the production of Gemcitabine, which is a nucleoside analog used to treat various types of cancer, including pancreatic, non-small cell lung, bladder, and breast cancer. The compound's role in the synthesis process is to provide a more accessible and efficient route to the final drug product, ultimately contributing to the development of effective cancer treatments.
Used in Research and Development:
In addition to its application in the pharmaceutical industry, 4-Amino-1-3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone is also used in research and development for the study of nucleoside analogs and their potential applications in cancer therapy. Researchers utilize this compound to investigate the mechanisms of action, pharmacokinetics, and potential side effects of Gemcitabine and other related antitumor agents. This helps in the development of new and improved cancer treatments, as well as in understanding the underlying biology of cancer cells and their response to therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 134790-40-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,7,9 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134790-40:
(8*1)+(7*3)+(6*4)+(5*7)+(4*9)+(3*0)+(2*4)+(1*0)=132
132 % 10 = 2
So 134790-40-2 is a valid CAS Registry Number.
InChI:InChI=1/C23H19F2N3O6/c24-23(25)18(34-20(30)15-9-5-2-6-10-15)16(13-32-19(29)14-7-3-1-4-8-14)33-21(23)28-12-11-17(26)27-22(28)31/h1-12,16,18,21H,13H2,(H2,26,27,31)/t16-,18+,21-/m1/s1
134790-40-2Relevant articles and documents
A miazines new compounds
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Paragraph 0007; 0010; 0011, (2017/07/07)
The invention relates to a new pyrimidine compound. The experiment proves that the new compound disclosed in the specification can inhibit growth of tumor cells, and has favorable effectiveness and safety when being used for preparing antineoplastic drugs. The vessel irritation experiment proves that the new compound does not have hemolysis or irritation and can be prepared into an injection for clinical use.
