134837-12-0

Basic information

• Product Name: 3-phenyl-5-(n-pentyl)isoxazole
• Synonyms: 3-phenyl-5-(n-pentyl)isoxazole
• CAS NO: 134837-12-0
• Molecular Weight: 215.295
• Mol File: 134837-12-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-phenyl-5-(n-pentyl)isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-5-(n-pentyl)isoxazole(134837-12-0)
• EPA Substance Registry System: 3-phenyl-5-(n-pentyl)isoxazole(134837-12-0)

Safety Data

• Hazardous Substances Data: 134837-12-0(Hazardous Substances Data)

Upstream product

• 873-67-6 benzonitrile oxide 
• 449181-08-2 3-phenyl-5-(n-pentyl)-5-hydroxy-2-isoxazoline 
• 628-71-7 1-Heptyne 
• 932-90-1 Benzaldoxime 
• 100-52-7 benzaldehyde 
• 27259-10-5 1-phenyloct-2-yn-1-one 
• 98-88-4 benzoyl chloride 
• 611-73-4 Benzoylformic acid 
• 25327-36-0 (Z)-2-(hydroxyimino)-2-phenylacetic acid 
• 698-16-8 benzohydroximoyl chloride 

Relevant articles and documents

Green preparation method of isoxazole compound participating in water-soluble vitamin E

The invention provides a green synthesis method of an isoxazole compound represented by the formula (III), wherein the aldehyde oxime compound represented by the formula (I) is a substrate and is in an aqueous solution of a surfactant with a mass concentration 1 wt % - 5 wt % in N - chlorosuccinimide. The alkyne compound represented by the formula (II) is reacted 6 - 16h at room temperature under the common action of the basic substance, and the resulting reaction solution is post-treated to obtain the isoxazole compound represented by the formula (III). Water serves as a reaction solvent, the use amount of the organic solvent is reduced, and zero emission of the solvent is realized.

Complementary regioselective synthesis of 3,5-disubstituted isoxazoles from ynones

Two regioselective synthetic routes towards 3,5-disubstituted isoxazoles from ynones are reported. One route takes place via first converting the ynones to ynone O-methyl oximes, followed by a palladium-catalyzed intramolecular cyclization. The other invo

An environmentally benign synthesis of isoxazolines and isoxazoles mediated by potassium chloride in water

An effective and environmentally benign procedure for the synthesis of isoxazolines and isoxazoles has been developed by a cycloaddition of nitrile oxides with alkenes or alkynes in water. In this approach, potassium chloride is first oxidized into chlorine in water by the environmentally friendly oxidant Oxone, then aldoximes are oxidized into nitrile oxides by the in situ generated hypochlorous acid, finally a 1,3-dipolar cycloaddition between nitrile oxides and alkenes or alkynes occurs to provide the corresponding isoxazolines and isoxazoles in good yields.