134860-27-8

Basic information

• Product Name: 1-<(S)-1-Phenylethyl>-2,5-(R,R)-bis(methoxycarbonyl)pyrrolidine
• Synonyms: 1-<(S)-1-Phenylethyl>-2,5-(R,R)-bis(methoxycarbonyl)pyrrolidine
• CAS NO: 134860-27-8
• Molecular Weight: 291.347
• Mol File: 134860-27-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-<(S)-1-Phenylethyl>-2,5-(R,R)-bis(methoxycarbonyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<(S)-1-Phenylethyl>-2,5-(R,R)-bis(methoxycarbonyl)pyrrolidine(134860-27-8)
• EPA Substance Registry System: 1-<(S)-1-Phenylethyl>-2,5-(R,R)-bis(methoxycarbonyl)pyrrolidine(134860-27-8)

Safety Data

• Hazardous Substances Data: 134860-27-8(Hazardous Substances Data)

Upstream product

• 868-72-4 dimethyl (2R,5S)-2,5-dibromohexanedioate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 868-72-4 dimethyl rac-2,5-dibromohexanedioate 
• 134860-28-9 1-<(S)-1-Phenylethyl>-2,5-cis-bis(carboxy)pyrrolidine 
• 868-72-4 dimethyl 2,5-dibromohexanedioate 
• 134931-84-3 1-<(S)-1-Phenylethyl>-2,5-cis-bis(methoxycarbonyl)pyrrolidine 

Downstream Products

• 148812-16-2 (2R,5R)-1-((S)-1-Phenylethyl)-2,5-bis(hydroxymethyl)pyrrolidine 
• 1198569-61-7 dimethyl (5R)-2-(3-chloropropyl)-1-[(1S)-1-phenylethyl]pyrrolidine-2,5-dicarboxylate 
• 148905-19-5 (2R,5R)-1-((S)-1-Phenylethyl)-2,5-bis(methoxymethoxymethyl)pyrrolidine 
• 93713-35-0 (2R,5R)-2,5-Pyrrolidinedicarboxylic acid 
• 213984-02-2 1-[(S)-1-phenylethyl]-(2R,5R)-bis(triisopropylsiloxymethyl)pyrrolidine 
• 213983-93-8 1-[(S)-1-phenylethyl]-(2R,5R)-bis(tert-butyldimethylsiloxymethyl)pyrrolidine 

Relevant articles and documents

Synthesis of a conformationally rigid analogue of 2-aminoadipic acid containing an 8-azabicyclo[3.2.1]octane skeleton

A new, conformationally rigid analogue of 2-aminoadipic acid, 8-[(benzyloxy)carbonyl]-3-methylene-8-azabicyclo[3.2.1]octane-1,5-dicarboxylic acid, is synthesized from dimethyl rac-2,5-dibromohexanedioate. The key steps involve alkylation-cyclization of 1-

A convenient synthesis of enantiomeric pairs of 2,5-disubstituted pyrrolidines of C2-symmetry

By the use of (-)-1-phenylethylamine as a chiral auxiliary, three diastereomeric isomers of 2,5-bis(methoxycarbonyl)pyrrolidine derivatives are prepared from dimethyl rac-2,5-dibromadipate and separted by crystallization and chromatographic fractionation