134872-90-5

Basic information

• Product Name: 2(R),6(R),7(S),8(R) dimethyl 2-phenyl-1-aza-4-oxa<4.3.0^1,6>bicyclononan-5-one-7,8-dicarboxylate
• CAS NO: 134872-90-5
• Molecular Weight: 333.341
• Mol File: 134872-90-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(R),6(R),7(S),8(R) dimethyl 2-phenyl-1-aza-4-oxa<4.3.0^1,6>bicyclononan-5-one-7,8-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2(R),6(R),7(S),8(R) dimethyl 2-phenyl-1-aza-4-oxa<4.3.0^1,6>bicyclononan-5-one-7,8-dicarboxylate(134872-90-5)
• EPA Substance Registry System: 2(R),6(R),7(S),8(R) dimethyl 2-phenyl-1-aza-4-oxa<4.3.0^1,6>bicyclononan-5-one-7,8-dicarboxylate(134872-90-5)

Safety Data

• Hazardous Substances Data: 134872-90-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 121269-45-2 (R)-5-phenyl-3,4,5,6-tetrahydro-2H-1,4-oxazin-2-one 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 20989-17-7 (2S)-2-phenylglycinol 
• 412907-19-8 (5S)-N-(1'-benzotriazolylmethyl)-5-phenylmorpholin-2-one 
• 144896-92-4 (5S)-5-phenylmorpholin-2-one 

Relevant articles and documents

N-(1'-Benzotriazolylmethyl)-5-phenylmorpholin-2-one: A stable crystalline chiral azomethine ylid precursor

The crystalline adduct of (5S)-5-phenylmorpholin-2-one with formaldehyde and benzotriazole on treatment with acid generates an azomethine ylid which may be trapped with a range of dipolarophiles in yields superior to those using in situ generation methodology.

Development of a chiral stabilised azomethine ylid. A chiral relay system

The chiral, stabilised azomethine ylids (2) derived from (R)-2-phenylglycinol has been demonstrated to undergo enantioselective 1,3-dipolar cycloaddition reactions with a range of alkene and alkyne dipolarophiles.