134886-28-5Relevant articles and documents
Catalytic Pauson-Khand Reaction in Ethylene Glycol-Toluene: Activity, Selectivity, and Catalyst Recycling
Cabré, Albert,Verdaguer, Xavier,Riera, Antoni
, p. 3891 - 3896 (2018/07/21)
The use of ethylene glycol (15% v/v in toluene) as additive in the catalytic Pauson-Khand reaction (PKR) is reported. In most cases both the yield and selectivity were enhanced compared to standard protocols. Moreover, the immiscibility of ethylene glycol
Pauson-Khand reactions in a photochemical flow microreactor
Asano, Keisuke,Uesugi, Yuki,Yoshida, Jun-Ichi
, p. 2398 - 2401 (2013/06/27)
Pauson-Khand reactions were achieved at ambient temperature without any additive using a photochemical flow microreactor. The efficiency of the reaction was better than that in a conventional batch reactor, and the reaction could be operated continuously for 1 h.
Utilization of aldoses as a carbonyl source in cyclocarbonylation of enynes
Ikeda, Keiichi,Morimoto, Tsumoru,Kakiuchi, Kiyomi
supporting information; experimental part, p. 6279 - 6282 (2010/12/25)
Figure presented. The reaction of enynes with acetyl-masked aldoses in the presence of a rhodium(I) catalyst resulted in cyclocarbonylation, thus avoiding the direct use of carbon monoxide, to afford bicyclic cyclopentenones. In rhodium catalysis, aldoses serve as a carbon monoxide equivalent by donating their carbonyl moieties on the acyclic aldehyde form to enynes. A variety of aldoses, including d-glucose, d-mannose, d-galactose, d-xylose, and d-ribose, can be used as a carbonyl source. Using the method, a wide variety of enynes were cyclocarbonylated in 22-67% yields. An asymmetric variant also proceeded with moderate to high enantioselectivity.
