134938-94-6

Basic information

• Product Name: cis-1-methoxy-2-(methylamino)-7-aminomitosene
• CAS NO: 134938-94-6
• Molecular Weight: 348.359
• Mol File: 134938-94-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-1-methoxy-2-(methylamino)-7-aminomitosene(CAS DataBase Reference)
• NIST Chemistry Reference: cis-1-methoxy-2-(methylamino)-7-aminomitosene(134938-94-6)
• EPA Substance Registry System: cis-1-methoxy-2-(methylamino)-7-aminomitosene(134938-94-6)

Safety Data

• Hazardous Substances Data: 134938-94-6(Hazardous Substances Data)

Upstream product

• 801-52-5 porfiromycin 

Relevant articles and documents

7-Aminoaziridinomitosenes: Synthesis, Structure, and Chemistry

7-Aminoleucoaziridinomitosene (2a) has been proposed as a key intermediate in the reductive activation process for the antineoplastic agent, mitomycin C (1a).Little is known about 2a and its oxidised equivalent, 7-aminoaziridinomitosene (3a).An expedient electrochemical procedure for 3a and the corresponding N-methyl analogue 3b has been developed.NMR spectral studies of 3a in DMF-d7 and DMSO-d6 provided important information concerning the solution-state structure for this adduct.Factors controlling the aziridine ring-opening process under reductive and nonreductive conditions have been determined, as well as evidence for the intermediacy of 2a in the reductive activation cascade of 1a.