134947-26-5

Basic information

• Product Name: 3,5-bis(trifluoromethyl)-1-(pentafluorophenyl)pyrazole
• CAS NO: 134947-26-5
• Molecular Weight: 370.125
• Mol File: 134947-26-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-bis(trifluoromethyl)-1-(pentafluorophenyl)pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(trifluoromethyl)-1-(pentafluorophenyl)pyrazole(134947-26-5)
• EPA Substance Registry System: 3,5-bis(trifluoromethyl)-1-(pentafluorophenyl)pyrazole(134947-26-5)

Safety Data

• Hazardous Substances Data: 134947-26-5(Hazardous Substances Data)

Upstream product

• 1522-22-1 1,1,1,5,5,5-hexafluoroacetylacetone 
• 828-73-9 pentafluorophenyl hydrazine 

Relevant articles and documents

Formation and dehydration of a series of 5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazoles

Reaction of five (3-oxo-4,4,4-trifluorobutanoyl)heterocycles with hydrazine hydrate under mild conditions gave the corresponding 3-heterocyclyl-5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazoles. Thermal elimination of water from the 3-(thien-2-yl), 3-(pyridin-2-yl) and 3-(pyridin-4-yl) compounds readily gave the corresponding pyrazoles but acid catalysis was required to form 3-(benzothiazol-2-yl)-5-trifluoromethylpyrazole and 3-(1-methylbenzimidazol-2-yl)-5-trifluoromethylpyrazole. More forcing conditions were required for the analogous dehydration/aromatisations giving 3,5-bis(trifluoromethyl)-1-(4-nitrophenyl)pyrazole and 3,5-bis(trifluoromethyl)-1-pentafluorophenylpyrazole.