13501-95-6

Basic information

• Product Name: 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE
• Synonyms: 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE;2,3,4,5-Tetra-O-acetyl-D-xylononitrile;2-O,3-O,4-O,5-O-Tetra(acetyl)D-xylononitrile;D-Xylononitrile, 2,3,4,5-tetraacetate;Nsc42415;Xylononitrile, 2,3,4,5-tetraacetate, D-
• CAS NO: 13501-95-6
• Molecular Formula: C13H17NO8
• Molecular Weight: 315.28
• Mol File: 13501-95-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 435.7°Cat760mmHg
• Flash Point: 190.3°C
• Appearance: /
• Density: 1.253g/cm³
• Vapor Pressure: 8.59E-08mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE(13501-95-6)
• EPA Substance Registry System: 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE(13501-95-6)

Safety Data

• Hazardous Substances Data: 13501-95-6(Hazardous Substances Data)

Usage

General Description

2,3,4,5-Tetra-O-acetyl-D-xylonitrile is a chemical compound that is a derivative of D-xylonitrile, a naturally occurring alditol. It is a white solid with a molecular formula of CxHxNOx, and it is commonly used in organic synthesis and chemical research. 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE is known for its ability to undergo reactions such as reduction, acetylation, and oxidation, which makes it a versatile and valuable building block in the creation of other organic compounds. Its properties and reactivity make it suitable for various applications in the field of chemistry, particularly in the development of new pharmaceuticals and materials.

InChI:InChI=1/C13H17NO8/c1-7(15)19-6-12(21-9(3)17)13(22-10(4)18)11(5-14)20-8(2)16/h11-13H,6H2,1-4H3

Upstream product

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Relevant articles and documents

Cyclopentadienyl-ruthenium(II) and iron(II) organometallic compounds with carbohydrate derivative ligands as good colorectal anticancer agents

New ruthenium(II) and iron(II) organometallic compounds of general formula [(η5-C5H5)M(PP)Lc][PF6], bearing carbohydrate derivative ligands (Lc), were prepared and fully characterized and the crystal structures of five of those compounds were determined by X-ray diffraction studies. Cell viability of colon cancer HCT116 cell line was determined for a total of 23 organometallic compounds and SAR's data analysis within this library showed an interesting dependency of the cytotoxic activity on the carbohydrate moiety, linker, phosphane coligands, and metal center. More importantly, two compounds, 14Ru and 18Ru, matched oxaliplatin IC50 (0.45 μM), the standard metallodrug used in CC chemotherapeutics, and our leading compound 14Ru was shown to be significantly more cytotoxic than oxaliplatin to HCT116 cells, triggering higher levels of caspase-3 and -7 activity and apoptosis in a dose-dependent manner.

New dammarane-type saponins from the roots of panax notoginseng

Three new dammarane-type triterpenoid saponins, 1-3, were isolated and identified as (20S)-20-O-[β-D-xylopyranosyl-(1→6)-β-D- glucopyranosyl-(1→6)-β-D-glucopyranosyl]dammar-24-ene-3β, 6α,12β, 20-tetrol (1), (20S)-6-O-[(E)-but-2-enoyl-(1→6)-β- D-glucopyranosyl]dammar-24-ene-3β,6α,12β,20-tetrol (2), and (20S)-6-O-[β-D-xylopyranosyl-(1→2)-β-D-xylopyranosyl] dammar-24-ene-3β,6α,12β,20-tetrol (3) from the roots of Panax notoginseng (Burkill) F.H.Chen (Araliaceae). Their structures were elucidated on the basis of spectroscopic analyses, including 1D- and 2D-NMR techniques and HR-ESI-MS, as well as by acidic hydrolysis. Copyright