135034-10-5 Usage
Description
3-Chloro-6-iodopyridazine is an organic compound characterized by the presence of a pyridazine ring with a chlorine atom at the 3rd position and an iodine atom at the 6th position. It is a versatile intermediate in the synthesis of various chemical compounds and has potential applications in different industries due to its unique structural properties.
Uses
Used in Pharmaceutical Industry:
3-Chloro-6-iodopyridazine is used as a reactant in the Suzuki-Miyaura coupling reaction for the synthesis of complex organic molecules, particularly in the development of new pharmaceutical compounds. The Suzuki-Miyaura coupling is a widely used method for the formation of carbon-carbon bonds, which is essential in the creation of diverse molecular structures with potential therapeutic applications.
Used in Chemical Synthesis:
3-Chloro-6-iodopyridazine is used as a reactant in the synthesis of 6-Chloropyridazine-3-carbonitrile (C368635), which is an important intermediate in the production of various chemical compounds. The carbonitrile group in 6-Chloropyridazine-3-carbonitrile can be further functionalized or used as a building block for the development of new molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 135034-10-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,0,3 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135034-10:
(8*1)+(7*3)+(6*5)+(5*0)+(4*3)+(3*4)+(2*1)+(1*0)=85
85 % 10 = 5
So 135034-10-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H2ClIN2/c5-3-1-2-4(6)8-7-3/h1-2H
135034-10-5Relevant articles and documents
Desymmetrization of dichloroazaheterocycles
Goodman, Allan J.,Stanforth, Stephen P.,Tarbit, Brian
, p. 15067 - 15070 (1999)
3,6-Dichloropyridizine 1a was converted in good yield into its mono-iodo derivative 1b when treated with a mixture of hydriodic acid and sodium iodide. Pure samples of the mono-iodo derivatives 2b, 3b and 4b could not be obtained from their corresponding dichlorinated precursors with these reagents. Compounds 1b and 4b underwent palladium catalysed Suzuki, Sonogashira and other coupling reactions.
13C nuclear magnetic resonance spectra of 3,6-disubstituted pyridazines
Heinisch,Holzer
, p. 972 - 977 (1991)
-
PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS
-
Page/Page column 55, (2016/05/24)
Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS
-
Page/Page column 89, (2016/12/22)
Polycyclic derivatives of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.