135041-24-6

Basic information

• Product Name: 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine
• Synonyms: 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine;6-S-(4-Methylphenyl)-6-thio-xanthosine 2',3',5'-Triacetate
• CAS NO: 135041-24-6
• Molecular Formula: C₂₃H₂₄N₄O₈S
• Molecular Weight: 516.52366
• Product Categories: 5-FOA;Bases & Related Reagents;Nucleotides
• Mol File: 135041-24-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 94-97°C
• Appearance: /
• Density: 1.52±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform, Ethyl Acetate
• PKA: 7.42±0.40(Predicted)
• CAS DataBase Reference: 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine(135041-24-6)
• EPA Substance Registry System: 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine(135041-24-6)

Safety Data

• Hazardous Substances Data: 135041-24-6(Hazardous Substances Data)

Usage

Description

6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine, with the CAS number 135041-24-6, is a complex organic compound characterized by its white foam appearance. It is primarily utilized in the field of organic synthesis, where its unique chemical structure contributes to the creation of various other compounds.

Uses

Used in Organic Synthesis:
6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine is used as a key intermediate in organic synthesis for the development of new chemical entities. Its application is driven by its distinctive structure, which allows for further functionalization and the creation of a diverse range of molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine is used as a building block for the synthesis of novel therapeutic agents. Its unique chemical properties make it a valuable component in the design and development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Research:
6-[(4-Methylphenyl)thio]-2-oxo-9-(2’,3’,5’-tri-O-acetyl--D-ribofuranosyl)-2,3-dihydropurine also serves as an important compound in chemical research, where it can be used to study various reaction mechanisms and explore new synthetic routes. Its application in research aids in the advancement of chemical knowledge and the discovery of innovative chemical processes.

Upstream product

• 135041-23-5 2-Amino-6-<(4-methylphenyl)thio>-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine 
• 16321-99-6 2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine 
• 106-45-6 para-thiocresol 

Downstream Products

• 1818-71-9 isoguanosine 
• 24386-79-6 6,6-Di-N-Methylisoguanosine 
• 29217-92-3 6-N-Phenylisoguanosine 
• 23605-76-7 6-N-Methylisoguanosine 
• 135041-25-7 2',3'-O-Isopropylidene-6-<(4-methylphenyl)thio>-2-oxo-9-(β-D-ribofuranosyl)-2,3-dihydropurine 

Relevant articles and documents

Conversion of Guanosine into Isoguanosine and Derivatives

Treatment of 2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine 7, which is readily prepared from guanosine 2 in two steps, with toluene-4-thiol and triethylamine followed by sodium nitrite in aqueous acetic acid gives 6-(4-methylphenyl)thio