1350648-04-2Relevant articles and documents
Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: Discovery of quinoxaline-based hybrid compounds with AChE, H 3R and BACE 1 inhibitory activities
Huang, Wenhai,Tang, Li,Shi, Ying,Huang, Shufang,Xu, Lei,Sheng, Rong,Wu, Peng,Li, Jia,Zhou, Naiming,Hu, Yongzhou
experimental part, p. 7158 - 7167 (2012/02/05)
A novel series of quinoxaline derivatives, as Multi-Target-Directed Ligands (MTDLs) for AD treatment, were designed by lending the core structural elements required for H3R antagonists and hybridizing BACE 1 inhibitor 1 with AChE inhibitor BYYT