1350711-72-6

Basic information

• Product Name: (4R)-4-benzyl-3-{[(1R,2R)-2-(4-bromophenyl)-4-oxocyclohexyl]carbonyl}-1,3-oxazolidin-2-one
• Synonyms: (4R)-4-benzyl-3-{[(1R,2R)-2-(4-bromophenyl)-4-oxocyclohexyl]carbonyl}-1,3-oxazolidin-2-one
• CAS NO: 1350711-72-6
• Molecular Weight: 456.336
• Mol File: 1350711-72-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4R)-4-benzyl-3-{[(1R,2R)-2-(4-bromophenyl)-4-oxocyclohexyl]carbonyl}-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-benzyl-3-{[(1R,2R)-2-(4-bromophenyl)-4-oxocyclohexyl]carbonyl}-1,3-oxazolidin-2-one(1350711-72-6)
• EPA Substance Registry System: (4R)-4-benzyl-3-{[(1R,2R)-2-(4-bromophenyl)-4-oxocyclohexyl]carbonyl}-1,3-oxazolidin-2-one(1350711-72-6)

Safety Data

• Hazardous Substances Data: 1350711-72-6(Hazardous Substances Data)

Upstream product

• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 38053-91-7 2-trimethylsilyloxy-1,3-butadiene 
• 7345-79-1 2-bromocinnamic acid 
• 27465-66-3 4-bromocinnamoyl chloride 
• 1200-07-3 trans-4-bromocinnamic acid 

Downstream Products

• 1350712-01-4 (1R,2R)-2-(4-bromophenyl)-N-[(R)-(4-chlorophenyl)-(4-pyridyl)methyl]-4-oxo-cyclohexanecarboxamide trifluoroacetate 
• 1350712-07-0 4-[(3R,4R)-3-(4-bromophenyl)-4-carboxy-(R)-1-methylcyclohexyl]morpholin-4-ium trifluoroacetate 
• 1350710-24-5 (1R,2R,4R)-N-[bis(4-fluorophenyl)methyl]-2-(4-bromophenyl)-4-(morpholin-4-yl)cyclohexanecarboxamide 
• 1350710-23-4 (1R,2R,4R)-2-(4-bromophenyl)-N-[(4-chlorophenyl)((S)-2-fluoropyridin-4-yl)methyl]-4-morpholin-4-ylcyclohexanecarboxamide 
• 1350710-22-3 (1R,2R,4R)-2-(4-bromophenyl)-N-[(4-chlorophenyl)((R)-2-fluoropyridin-4-yl)methyl]-4-morpholin-4-ylcyclohexanecarboxamide 
• 1350710-16-5 (1R,2R,4R)-2-(4-bromophenyl)-N-[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]-4-morpholino-cyclohexanecarboxamide trifluoroacetate 
• 1350710-14-3 (1R,2R,4S)-2-(4-bromophenyl)-N-[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]-4-morpholino-cyclohexanecarboxamide trifluoroacetate 
• 1350711-98-6 (1R,2R)-2-(4-bromophenyl)-N-(1-(4-chlorophenyl)-2,2,2-trifluoroethyl)-4-oxocyclohexanecarboxamide 
• 1350711-82-8 (1R,2R,4R)-2-(4-bromophenyl)-4-morpholin-4-ylcyclohexanecarboxylic acid hydrochloride 
• 1350711-78-2 methyl (1R,2R,4R)-2-(4-bromophenyl)-4-morpholin-4-ylcyclohexanecarboxylate 
• 1350711-80-6 methyl (1R,2R,4R)-2-(4-bromophenyl)-4-morpholin-4-ylcyclohexanecarboxylate 
• 1350711-76-0 methyl (1R,2R)-2-(4-bromophenyl)-4-oxocyclohexanecarboxylate 
• 1350711-68-0 (1R,2R)-2-(4-bromophenyl)-4-oxocyclohexanecarboxylic acid 
• 1350711-40-8 4-[(1R,3R,4R)-4-{[bis(4-fluorophenyl)methyl]carbamoyl}-3-(4-cyanophenyl)cyclohexyl]-morpholine trifluoroacetate 

Relevant articles and documents

Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors

The synthesis, SAR, binding affinities and pharmacokinetic profiles are described for a series of cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors discovered by high throughput screening. Compounds show high levels of ex vivo target engagement in mouse plasma 20 h post oral dose.