1350744-91-0

Basic information

• Product Name: N-[(2S)-2-(4-isobutylphenyl)propionyl]-7,8-difluoro-(3S)-3-methyl-2,3-dihydro-4H-[1,4]benzoxazine
• CAS NO: 1350744-91-0
• Molecular Weight: 373.443
• Mol File: 1350744-91-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(2S)-2-(4-isobutylphenyl)propionyl]-7,8-difluoro-(3S)-3-methyl-2,3-dihydro-4H-[1,4]benzoxazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2S)-2-(4-isobutylphenyl)propionyl]-7,8-difluoro-(3S)-3-methyl-2,3-dihydro-4H-[1,4]benzoxazine(1350744-91-0)
• EPA Substance Registry System: N-[(2S)-2-(4-isobutylphenyl)propionyl]-7,8-difluoro-(3S)-3-methyl-2,3-dihydro-4H-[1,4]benzoxazine(1350744-91-0)

Safety Data

• Hazardous Substances Data: 1350744-91-0(Hazardous Substances Data)

Upstream product

• 106939-42-8 (S)-7,8-difluoro-3,4-dihydro-3-methyl-2H-1,4-benzoxazine 
• 115588-20-0 (2S)-2-(4-isobutylphenyl)-propionyl chloride 
• 71381-91-4 (+/-)-2-(4-isobutylphenyl)propanoyl chloride 
• 51146-56-6 (S)-ibuprofen 
• 15687-27-1 ibuprofen 

Relevant articles and documents

2-Arylpropionyl chlorides in kinetic resolution of racemic 3-methyl-2,3-dihydro-4H-[1,4]benzoxazines

Kinetic resolution of racemic 3-methyl-2,3-dihydro-4H-[1,4]benzoxazines in the reaction with chiral 2-arylpropionyl chloride predominantly yielded R*,R*-diastereomers. Ibuprofen acyl chloride as acylating agent was found to be more selective and sensitive