1350765-34-2Relevant articles and documents
Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2
Ortiz Zacarías, Natalia V.,Chahal, Kirti K.,?imková, Tereza,Van Der Horst, Cas,Zheng, Yi,Inoue, Asuka,Theunissen, Emy,Mallee, Lloyd,Van Der Es, Daan,Louvel, Julien,Ijzerman, Adriaan P.,Handel, Tracy M.,Kufareva, Irina,Heitman, Laura H.
, p. 2608 - 2621 (2021/03/09)
Covalently acting inhibitors constitute a large and growing fraction of approved small-molecule therapeutics as well as useful tools for a variety of in vitro and in vivo applications. Here, we aimed to develop a covalent antagonist of CC chemokine recept