1350852-88-8

Basic information

• Product Name: 4-amino-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one
• Synonyms: 4-amino-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one
• CAS NO: 1350852-88-8
• Molecular Weight: 536.892
• Mol File: 1350852-88-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one(1350852-88-8)
• EPA Substance Registry System: 4-amino-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one(1350852-88-8)

Safety Data

• Hazardous Substances Data: 1350852-88-8(Hazardous Substances Data)

Upstream product

• 95-79-4 5-chloro-2-methyl-benzenamine 
• 61072-56-8 4-chloro-2-fluorobenzaldehyde 
• 698-25-9 6-chloro-1H-indazole 
• 503045-59-8 6-chloro-3-iodo-1H-indazole 
• 885278-30-8 6-chloro-1H-indazole-3-carbonitrile 
• 1350855-87-6 6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazole-3-carbonitrile 

Downstream Products

• 1350854-36-2 2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-4-(methylamino)-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one 
• 1350856-26-6 4-bromo-2-[6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl]-5-methyl-5-phenyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one 

Relevant articles and documents

SOLUBLE GUANYLATE CYCLASE ACTIVATORS

A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I , or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the above mentioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof