1350894-60-8Relevant articles and documents
Access to saturated fused pyrimidine derivatives via a flexible N -vinyl tertiary enamide synthesis
Estrada, Anthony A.,Lyssikatos, Joseph P.,St-Jean, Frédéric,Bergeron, Philippe
, p. 2387 - 2391 (2011/10/30)
An array of tetrasubstituted saturated fused pyrimidines has been synthesized through two-sequential, simple, and efficient one-pot operations. The strategic utilization of the N-PMB group proved critical in the ability to construct a broad range of N-vinyl tertiary enamide starting materials. This stands as a flexible approach to functionalized pyrimidines with the capability of manipulating either ketone, acid chloride, or nitrile reaction partners. Georg Thieme Verlag Stuttgart - New York.