1351167-82-2

Basic information

• Product Name: 1-bromo-2-fluoro-5-methyl-4-(methylsulfonyl)benzene
• Synonyms: 1-bromo-2-fluoro-5-methyl-4-(methylsulfonyl)benzene
• CAS NO: 1351167-82-2
• Molecular Weight: 267.119
• Mol File: 1351167-82-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-bromo-2-fluoro-5-methyl-4-(methylsulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-fluoro-5-methyl-4-(methylsulfonyl)benzene(1351167-82-2)
• EPA Substance Registry System: 1-bromo-2-fluoro-5-methyl-4-(methylsulfonyl)benzene(1351167-82-2)

Safety Data

• Hazardous Substances Data: 1351167-82-2(Hazardous Substances Data)

Upstream product

• 1351167-83-3 (4-bromo-5-fluoro-2-methylphenyl)(methyl)sulfane 
• 52723-82-7 4-bromo-5-fluoro-2-methylaniline 

Downstream Products

• 1351166-47-6 (S)-1-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)pyrrolidin-2-one 
• 1351168-04-1 (S)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)-1-(piperidin-4-yl)pyrrolidin-2-one 
• 1351166-09-0 (S)-1-(1-(5-chloropyrazin-2-yl)piperidin-4-yl)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)pyrrolidin-2-one 
• 1351166-10-3 (S)-1-(1-(5-ethylpyrazin-2-yl)piperidin-4-yl)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)pyrrolidin-2-one 
• 1351166-69-2 (S)-1'-(5-ethylpyrimidin-2-yl)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)-[1,4'-bipiperidin]-2-one 
• 1351168-03-0 (S)-benzyl 4-(3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)-2-oxopyrrolidin-1-yl)piperidin-1-carboxylate 
• 1433881-01-6 (S)-3-(2-fluoro-5-methyl-4-(methylsulfonyl)phenylamino)-1-(1-(3-isopropyl-1,2,4-thiadiazol-5-yl)piperidin-4-yl)pyrrolidin-2-one 

Relevant articles and documents

SULFONE DERIVATIVES

The present invention provides compounds of formula (I) wherein X1, X2, X3, X4, R1, R1a, R1b, R2', R2 , R3', R3 , R6 and R7 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which X1, X2, L, R3, R4, R5, R6, R6a, R7, R9, R9a, and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.