1351373-47-1

Basic information

• Product Name: Bis-Propargyl-PEG10
• Synonyms: Bis-Propargyl-PEG10
• CAS NO: 1351373-47-1
• Molecular Formula: C24H42O10
• Molecular Weight: 490.58428
• Mol File: 1351373-47-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 529.5±45.0 °C(Predicted)
• Appearance: /
• Density: 1.076±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Bis-Propargyl-PEG10(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-Propargyl-PEG10(1351373-47-1)
• EPA Substance Registry System: Bis-Propargyl-PEG10(1351373-47-1)

Safety Data

• Hazardous Substances Data: 1351373-47-1(Hazardous Substances Data)

Usage

Description

Bis-Propargyl-PEG10 is a synthetic molecule that features two propargyl groups and a polyethylene glycol (PEG) chain with an average molecular weight of 10 kDa. It is designed to be highly reactive with azide-bearing compounds or biomolecules through copper-catalyzed Click Chemistry, allowing for the efficient formation of stable triazole linkages. The incorporation of PEG units into the molecule enhances its solubility in aqueous environments, making it a versatile building block for various applications in chemical biology and materials science.

Uses

Used in Chemical Biology:
Bis-Propargyl-PEG10 is used as a molecular linker for the conjugation of biomolecules, such as proteins, peptides, and nucleic acids, to other molecules or surfaces. The expression is: Bis-Propargyl-PEG10 is used as a molecular linker for [application reason], which is to facilitate the formation of stable covalent bonds with azide-modified biomolecules through copper-catalyzed Click Chemistry, enabling the creation of diverse bioconjugates for research and therapeutic applications.
Used in Drug Delivery Systems:
Bis-Propargyl-PEG10 is used as a component in the design of drug delivery systems, particularly for the development of targeted therapies. The expression is: Bis-Propargyl-PEG10 is used as a targeting moiety for [application reason], which is to enhance the solubility and bioavailability of drug molecules, as well as to provide a platform for the attachment of targeting ligands that can direct the drug to specific cells or tissues, thereby improving the therapeutic efficacy and reducing side effects.
Used in Materials Science:
Bis-Propargyl-PEG10 is used as a building block for the synthesis of functional materials, such as hydrogels, micelles, and nanoparticles. The expression is: Bis-Propargyl-PEG10 is used as a building block for [application reason], which is to take advantage of its reactivity in Click Chemistry to create well-defined, stimuli-responsive, and biocompatible materials with tailored properties for various applications, including drug delivery, tissue engineering, and diagnostics.
Used in Diagnostics:
Bis-Propargyl-PEG10 is used as a component in the development of diagnostic tools, such as imaging agents and sensors. The expression is: Bis-Propargyl-PEG10 is used as a diagnostic component for [application reason], which is to leverage its reactivity with azide-modified probes or markers to enable the specific detection and visualization of biological targets, providing valuable information for disease diagnosis and monitoring.