135144-52-4Relevant articles and documents
Synthesis of the Monofluoro Ketone Peptide Isostere
Garrett, Garry S.,Emge, Thomas J.,Lee, Susannie C.,Fischer, Elaine M.,Dyehouse, Karyn,McIver, John M.
, p. 4823 - 4826 (2007/10/02)
A synthetic method for the construction of monofluoro ketone peptide isosteres has been realized.The methodology has been employed in a synthesis of the fluoro ketone replacement for the natural substrate for D,D-carboxypeptidase-transpeptidase.