1351472-16-6

Basic information

• Product Name: C₃₄H₄₄O₆
• Synonyms: C₃₄H₄₄O₆
• CAS NO: 1351472-16-6
• Molecular Weight: 548.72
• Mol File: 1351472-16-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₄H₄₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₄₄O₆(1351472-16-6)
• EPA Substance Registry System: C₃₄H₄₄O₆(1351472-16-6)

Safety Data

• Hazardous Substances Data: 1351472-16-6(Hazardous Substances Data)

Upstream product

• 1351472-15-5 2-allyl-3-(carbomethoxy)benzyloxybenzaldehyde 
• 223734-62-1 2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran 

Relevant articles and documents

TREPROSTINIL PRODUCTION

A method is disclosed for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction using a chiral inducing agent. Also described are methods of preparing treprostinil or a pharmaceutically acceptable salt thereof comprising the alkyne addition reaction as well as novel intermediates useful for synthesis prostacyclin derivatives. A functional alcohol protecting group protects the alcohol group from participating in reactions that are occurring in other parts of the molecule. The intermediate is later deprotected prior to conversion and hydrolyzing to obtain the final treprostinil product.