1351564-29-8

Basic information

• Product Name: (R)-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
• Synonyms: (R)-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
• CAS NO: 1351564-29-8
• Molecular Weight: 437.301
• Mol File: 1351564-29-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one(1351564-29-8)
• EPA Substance Registry System: (R)-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one(1351564-29-8)

Safety Data

• Hazardous Substances Data: 1351564-29-8(Hazardous Substances Data)

Upstream product

• 1351564-27-6 3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-3-en-1-one 
• 1351564-28-7 3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 
• 1351564-26-5 4-hydroxy-3-nitro-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 
• 762240-92-6 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 

Downstream Products

• 654671-78-0 (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate 
• 486460-32-6 sitagliptin 

Relevant articles and documents

A NOVEL SYNTHETIC APPROACH TO ?-AMINOBUTYRYL SUBSTITUTED COMPOUNDS

The present invention relates to process to prepare β-aminobutyryl compounds of formula (I), wherein Q is N, CH, C-CF3 or C-phenyl, preferably N, and R10 is H, C1-C4-alkyl or fluorinated C1C2-alkyl, preferably trifluoromethyl, and wherein X is halogen selected from fluoro, chloro, or bromo, preferably fluoro, same or different, and n is 1-4.