1351858-27-9

Basic information

• Product Name: 1-(4-bromophenyl)4-(2-chloropyridin-3-yl)aminophthalazine
• CAS NO: 1351858-27-9
• Molecular Weight: 411.688
• Mol File: 1351858-27-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-bromophenyl)4-(2-chloropyridin-3-yl)aminophthalazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)4-(2-chloropyridin-3-yl)aminophthalazine(1351858-27-9)
• EPA Substance Registry System: 1-(4-bromophenyl)4-(2-chloropyridin-3-yl)aminophthalazine(1351858-27-9)

Safety Data

• Hazardous Substances Data: 1351858-27-9(Hazardous Substances Data)

Upstream product

• 2159-40-2 2-(4-bromobenzoyl)benzoic acid 
• 76462-38-9 1,2-dihydro-4-(4-bromophenyl)(2H)phthalazin-1-one 
• 6298-19-7 2-chloro-3-aminopyridine 
• 133958-68-6 1-chloro-4-(4-bromophenyl)phthalazine 

Relevant articles and documents

Synthesis and evaluation of anti-proliferative activity of 1,4-disubstituted phthalazines

A series of new phthalazine derivatives 3a-i and 4a-c were synthesized via the reaction of 1-chlorophthalazine derivative 2 with either N-substituted-piperazines, primary or their secondary amines. The structure of the synthesized, new compounds were characterized by spectral data. The anti-proliferative activity on human breast cancer cell line MCF-7 of the synthesized compounds was determined. The results showed that six of the test compounds (3a, 3g, 3i, and 4a-c) displayed potent cytotoxic activity ranging from 1.4 to 2.3 μmol.