135204-38-5

Basic information

• Product Name: (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine
• Synonyms: (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine
• CAS NO: 135204-38-5
• Molecular Weight: 253.365
• Mol File: 135204-38-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine(135204-38-5)
• EPA Substance Registry System: (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine(135204-38-5)

Safety Data

• Hazardous Substances Data: 135204-38-5(Hazardous Substances Data)

Upstream product

• 16854-32-3 (1S,2S)-(+)-thiomicamine 
• 67-64-1 acetone 

Downstream Products

• 135204-34-1 (4S,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-55-6 (4R,5S)-4-(acetoxymethyl)-3-acetyl-2,2-dimethyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-37-4 (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-35-2 (4R,5S)-3-acetyl-2,2-dimethyl-4-formyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-36-3 (4S,5S)-3-acetyl-2,2-dimethyl-4-formyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 27348-48-7 (+)-(1S,2R)-2-amino-1-<4-(methylthio)phenyl>-1,3-propanediol 
• 135761-10-3 Acetic acid (R)-2-methyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-4-ylmethyl ester; compound with methanesulfonic acid 
• 23150-35-8 (R*,R*)-(+)-thiomicamine 
• 135204-33-0 (4S,5S)-5-(4-methylthiophenyl)-4-acetoxymethyl-3-acetyl-2,2-dimethyl-1,3-oxazolidine 

Relevant articles and documents

Direct Conversion of (1S,2S)-2-Amino-1--1,3-propanediol into Its Enantiomer for Efficient Synthesis of Thiamphenicol and Florfenicol

The usual synthesis of thiamphenicol and florfenicol involves the resolution of racemic threo-2-amino-1--1,3-propanediol into its 1S,2S and 1R,2R isomers ((+)-3 and (-)-3), of which only the latter is a useful precursor.An efficient conversion of the 1S,2S isomer into the 1R,2R enantiomer in high yield, is described.