1352127-75-3

Basic information

• Product Name: 4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane
• Synonyms: 4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane
• CAS NO: 1352127-75-3
• Molecular Weight: 274.211
• Mol File: 1352127-75-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane(1352127-75-3)
• EPA Substance Registry System: 4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane(1352127-75-3)

Safety Data

• Hazardous Substances Data: 1352127-75-3(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 82954-89-0 ethylboronic acid pinacol ester 
• 1352127-71-9 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate 
• 246021-86-3 C₆H₅CH₂CH₂CH(Sn(CH₂CH₂CH₂CH₃)3)OCON(CH(CH₃)2)2 
• 122-97-4 3-Phenyl-1-propanol 
• 1352127-71-9 (S)-3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate 
• 218601-55-9 3-phenylpropyl N,N-diisopropylcarbamate 

Downstream Products

• 1992-50-3 1-phenylpentan-3-ol 
• 105836-17-7 (R)-1-phenyl-3-pentanol 
• 71747-37-0 (S)-1-phenylpentan-3-ol 

Relevant articles and documents

Synthesis of α-Chiral Ketones and Chiral Alkanes Using Radical Polar Crossover Reactions of Vinyl Boron Ate Complexes

Vinyl boron ate complexes of enantioenriched secondary alkyl pinacolboronic esters undergo stereospecific radical-induced 1,2-migration in radical polar crossover reactions. In this three-component process various commercially available alkyl iodides act as radical precursors and light is used for chain initiation. Subsequent oxidation and protodeborylation leads to valuable α-chiral ketones and chiral alkanes, respectively, with excellent enantiopurity.

Lithiated carbamates: Chiral carbenoids for iterative homologation of boranes and boronic esters

(Chemical Equation Presented) Take your pick: Either enantiomer of either diastereomer of substrates bearing adjacent stereogenic centers is accessible through reaction of an (R)- or (S)-lithiated carbamate with an (R)- or (S)-boronic ester (see scheme; pin = pinacolate, OCb = substituted carbamate).