1352299-27-4

Basic information

• Product Name: methyl 2,3,4-tri-O-benzyl-6-O-{4-[2-(2-(tridecafluorohexanecarboxamido)ethoxy)ethoxy]phenyl}-α-D-glucopyranoside
• Synonyms: methyl 2,3,4-tri-O-benzyl-6-O-{4-[2-(2-(tridecafluorohexanecarboxamido)ethoxy)ethoxy]phenyl}-α-D-glucopyranoside
• CAS NO: 1352299-27-4
• Molecular Weight: 989.825
• Mol File: 1352299-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,3,4-tri-O-benzyl-6-O-{4-[2-(2-(tridecafluorohexanecarboxamido)ethoxy)ethoxy]phenyl}-α-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,4-tri-O-benzyl-6-O-{4-[2-(2-(tridecafluorohexanecarboxamido)ethoxy)ethoxy]phenyl}-α-D-glucopyranoside(1352299-27-4)
• EPA Substance Registry System: methyl 2,3,4-tri-O-benzyl-6-O-{4-[2-(2-(tridecafluorohexanecarboxamido)ethoxy)ethoxy]phenyl}-α-D-glucopyranoside(1352299-27-4)

Safety Data

• Hazardous Substances Data: 1352299-27-4(Hazardous Substances Data)

Upstream product

• 53936-56-4 4-(tetrahydro-2H-2-pyranyloxy)phenol 
• 375-85-9 perfluoroheptanoic acid 
• 52447-22-0 perfluoroheptanoyl chloride 
• 1352299-25-2 4-[2-(2-azidoethoxy)ethoxy]phenol 

Relevant articles and documents

A fluorous-assisted synthesis of oligosaccharides using a phenyl ether linker as a safety-catch linker

We report on the fluorous-assisted synthesis of oligosaccharides using a phenyl ether linker. The phenyl ether linker is stable under both acidic and basic conditions but can be cleaved under mildly acidic conditions after reduction to a vinyl ether. The utility of the method was demonstrated by the synthesis of a trisaccharide. A protected trisaccharide with a light-fluorous tag was directly prepared by one-pot glycosylation using three building blocks that contained a building block with a light-fluorous tag though a phenyl ether. A Birch reduction of the trisaccharide provided a fully deprotected trisaccharide with the fluorous tag attached through a vinyl ether, which was easily purified by solid-phase extraction. The tag was cleaved from the sugar portion by treatment with 3% TFA in MeOH.