135245-29-3

Basic information

• Product Name: 3'-monophosphate of adenosine
• Synonyms: 3'-monophosphate of adenosine
• CAS NO: 135245-29-3
• Molecular Weight: 345.208
• Mol File: 135245-29-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3'-monophosphate of adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-monophosphate of adenosine(135245-29-3)
• EPA Substance Registry System: 3'-monophosphate of adenosine(135245-29-3)

Safety Data

• Hazardous Substances Data: 135245-29-3(Hazardous Substances Data)

Upstream product

• 62906-30-3 adenosine 2′:3′-cyclic monophosphate 

Relevant articles and documents

Hydrolysis of diribonucleoside monophosphate diesters assisted by a manganese(II) complex

An Mn2+ complex with 2,2′:6′,2″-terpyridine (terpy) was found to promote the hydrolysis of NpN (NpN = diribonucleoside monophosphate diester) efficiently at pH 7.0 and 50 °C under ambient conditions. The structure of the Mn2+ complex involving a phosphodiester molecule, [(terpy)(dpp)MnII(μ-dpp) 2MnII(dpp)(terpy)], dpp = diphenyl phosphate anion, was established by X-ray crystallography, and the coordination mode of Mn 2+ to a phosphodiester molecule was considered.

REGIOSELECTIVE CLEAVAGE OF DI- AND POLY-RIBONUCLEOTIDES INDUCED BY CYCLODEXTRINS (CYCLOMALTO-OLIGOSACCHARIDES)

Cyclodextrins (cyclomalto-oligosaccharides, CDs) induce regioselective cleavage of the 3',5'-phosphodiester linkages in di- and poly-ribonucleotides at pH 11.08 and 50 deg C. 0.15M Cyclomaltohexaose (α-CD) mediates the cleavage of CpA, CpC, CpG, and CpU to give 96-97percent of cytidine 3'-phosphate together with adenosine, cytidine, guanosine, and uridine, respectively.In the absence of α-CD, 50-52percent of cytidine 2'-phosphate is formed as by-product. α-CD also promotes the formation of adenosine 3'-phosphate from ApA and ApC, guanosine 3'-phosphate from GpG, and uridine 3'-phosphate from UpU.In contrast, β-CD and γ-CD enhance the formation of the corresponding 2'-phosphates.Regioselective cleavages of poly, poly, poly, and poly are achieved also.