1352657-86-3Relevant articles and documents
Three-component coupling of arynes and organic bromides
Yoshida, Hiroto,Asatsu, Yuji,Mimura, Yasuhiro,Ito, Yu,Ohshita, Joji,Takaki, Ken
supporting information; experimental part, p. 9676 - 9679 (2011/12/05)
Magic trio: Arynes are easily coupled with neutral nucleophiles and organic bromides to afford functionalized bromoarenes depending upon the nucleophile (Nu). The three-component coupling proceeds through the formation of bromine ate complexes, and can be applied to the synthesis of multisubstituted isoquinolines and benzo[b]oxepines having pharmacological activity. Copyright