13528-93-3 Usage
Description
1,2-Bis(chlorodimethylsilyl)ethane, also known as a silylating reagent, is an organosilicon compound with the chemical formula (CH3)2SiClCH2CH2Si(CH3)2Cl. It is a transparent low melting solid with a melting point of 36-41°C and a boiling point of 198°C at 734 mmHg. 1,2-Bis(chlorodimethylsilyl)ethane is particularly useful in the protection of primary amines and has applications in various industries, including medicine, electronics, and polymer materials.
Uses
1. Used in Chemical Synthesis:
1,2-Bis(chlorodimethylsilyl)ethane is used as a protecting reagent for primary amines, forming tetramethyldisilylazacyclopentane or Stabase adducts. These adducts are stable under strongly basic conditions, making them suitable for use in the alkylation of substrates bearing a primary amine. This application is particularly attractive due to the ease of preparation, base stability, and facile removal of the protecting group.
2. Used in Medicine Field:
In the medical field, 1,2-Bis(chlorodimethylsilyl)ethane can be utilized in the synthesis of various pharmaceutical compounds, taking advantage of its silylating properties and ability to protect primary amines during chemical reactions.
3. Used in Electronics Industry:
The electronics industry can benefit from 1,2-Bis(chlorodimethylsilyl)ethane's properties as a silylating reagent, potentially using it in the development of new materials or components with specific characteristics.
4. Used in Polymer Material:
In the polymer material industry, 1,2-Bis(chlorodimethylsilyl)ethane can be employed to modify polymers or create new materials with enhanced properties, such as improved stability or reactivity.
5. Used in Combination with Zinc:
When combined with zinc, 1,2-Bis(chlorodimethylsilyl)ethane can form organozinc carbenoids, which are valuable intermediates in organic synthesis.
6. Used as an Electrophilic Silylating Reagent:
Due to its reactivity, 1,2-Bis(chlorodimethylsilyl)ethane can also be used as an electrophilic silylating reagent in various chemical reactions, further expanding its applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 13528-93-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,2 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13528-93:
(7*1)+(6*3)+(5*5)+(4*2)+(3*8)+(2*9)+(1*3)=103
103 % 10 = 3
So 13528-93-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H16Cl2Si2/c1-9(2,7)5-6-10(3,4)8/h5-6H2,1-4H3
13528-93-3Relevant articles and documents
Petrashko et al.
, p. 2300,2302 (1967)
Process for the preparation of halogenated 1,2-disilaethanes
-
, (2008/06/13)
A process for the preparation of halogenated 1,2-disilaethanes of the general formula X3?nRnSi—CHR1CHR1—SiRnX3?n??(I) in which R may be identical or different and denotes a hydrogen atom or a monovalent optionally substituted hydrocarbon radical having 1 to 40 carbon atom(s) per radical, R1may be identical or different and denotes a hydrogen atom or a monovalent optionally substituted hydrocarbon radical having 1 to 40 carbon atom(s) per radical, X denotes a halogen atom and n denotes 0, 1 or 2, wherein halogenated 1,2-disilaethenes of the general formula X3?nRnSi—CR1═CR1—SiRnX3?n??(II) in which R, R1, X and n have the meaning stated above therefor, are reacted with hydrogen in the presence of promoting catalysts. The product is produced in high yield and purity.
INVESTIGATION OF THE HYDROSILYLATION OF CHLOROETHYLENES AND THEIR SILYL-SUBSTITUTED DERIVATIVES BY MEANS OF NMR SPECTROSCOPY
Sheludyakov, V. D.,Lakhtin, V. G.,Nosova, V. M.,Stolyarova, O. V.,Kisin, A. V.,et al.
, p. 1146 - 1151 (2007/10/02)
-
