1352807-17-0Relevant articles and documents
Organocatalytic synthesis of 1,2,3-triazoles from unactivated ketones and arylazides
Belkheira, Mokhtaria,El Abed, Douniazad,Pons, Jean-Marc,Bressy, Cyril
supporting information; experimental part, p. 12917 - 12921 (2011/12/04)
Organo-click reaction: A new and complementary method to Huisgen's metal-catalyzed triazole synthesis is described using unactivated ketones and arylazides as the substrates and proline as an organocatalyst. Dramatic acceleration was observed for this reaction using microwave activation and high regio- and chemoselectivities were obtained for a wide range of ketones and arylazides (see scheme). Copyright