135339-02-5

Basic information

• Product Name: (2-fluoro-1-trifluoromethylindolizin-3-yl)phenylmethanone
• Synonyms: (2-fluoro-1-trifluoromethylindolizin-3-yl)phenylmethanone
• CAS NO: 135339-02-5
• Molecular Weight: 307.247
• Mol File: 135339-02-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-fluoro-1-trifluoromethylindolizin-3-yl)phenylmethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-fluoro-1-trifluoromethylindolizin-3-yl)phenylmethanone(135339-02-5)
• EPA Substance Registry System: (2-fluoro-1-trifluoromethylindolizin-3-yl)phenylmethanone(135339-02-5)

Safety Data

• Hazardous Substances Data: 135339-02-5(Hazardous Substances Data)

Upstream product

• 116-15-4 perfluoropropylene 
• 1137-94-6 1-(2-phenyl-2-oxoethyl)pyridinium iodide 
• 16883-69-5 N-phenacylpyridinium bromide 

Relevant articles and documents

FLUOROCARBON DERIVATIVES OF NITROGEN. PART 18. SYNTHESIS OF FLUORINATED INDOLIZINES THROUGH REACTIONS OF PYRIDINIUM ETHOXYCARBONYLMETHYLIDE OR PYRIDINIUM PHENACYLIDE WITH PERFLUOROPROPENE, PERFLUOROBUT-2-YNE AND 3,3,3-TRIFLUOROPROPYNE

3-Ethoxycarbonyl-2-fluoro-1-trifluoromethylindolizine (6), 3-ethoxycarbonyl-1,2-bis(trifluoromethyl)indolizine (8), 3-ethoxycarbonyl-1-trifluoromethylindolizine (10) and 3-ethoxycarbonyl-2-perfluoroheptylimidazopyridine (12) have been obtained via trapping of pyridinium ethoxycarbonylmethylide with perfluoropropane, perfluorobut-2-yne, 3,3,3-trifluoropropyne and perfluorooctanenitrile respectively.Similarly, 2-fluoro-1-trifluoromethyl-3-phenacylindolizine (7), 1,2-bis(trifluoromethyl)-3-phenacylindolizine (9), and 3-phenacyl-1-trifluoromethylindolizine (11), have been obtained via reaction of pyridinium phenacylide with perfluoropropene, perfluorobut-2-yne, and 3,3,3-trifluoropropyne respectively.Alkaline hydrolysis of (8) gave 1,2-bis(trifluoromethyl)indolizine-3-carboxylic acid (16), which was decarboxylated thermally to 1,2-bis(trifluoromethyl)indolizine (15).