135384-47-3

Basic information

• Product Name: (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-((R)-toluene-4-sulfinyl)-ethanol
• Synonyms: (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-((R)-toluene-4-sulfinyl)-ethanol
• CAS NO: 135384-47-3
• Molecular Weight: 337.442
• Mol File: 135384-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-((R)-toluene-4-sulfinyl)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-((R)-toluene-4-sulfinyl)-ethanol(135384-47-3)
• EPA Substance Registry System: (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-((R)-toluene-4-sulfinyl)-ethanol(135384-47-3)

Safety Data

• Hazardous Substances Data: 135384-47-3(Hazardous Substances Data)

Upstream product

• 128949-52-0 (R)-(+)-2-<(4-methylphenyl)sulfinylmethyl>pyridine 
• 100-52-7 benzaldehyde 

Downstream Products

• 2294-74-8 (-)-1-phenyl-2-(α-pyridyl)ethanol 
• 135417-41-3 (1R,2S)-1-Phenyl-2-pyridin-2-yl-2-p-tolylsulfanyl-ethanol 

Relevant articles and documents

ROLE OF HETEROCYCLES ON THE STEREOSELECTIVE REACTIONS OF α-SULFINYL CARBANIONS USING OPTICALLY ACTIVE 2-PYRIDYLMETHYL P-TOLYL AND 2-(N-METHYLIMIDAZOLYL)METHYL p-TOLYL SULFOXIDES WITH ALDEHYDES

Optically active 2-pyridylmethyl p-tolyl (1) and 2-(N-methylimidazolyl)methyl p-tolyl sulfoxides (2) were synthesised and the reactions of their chiral α-sulfinyl carbanions with aldehydes afforded stereoselectively the condensation products.The absolute configurations of the products were determined by X-ray crystallographic analysis and chemical reactions.The mechanism for the reaction is described.