1353891-99-2

Basic information

• Product Name: isopropyl 2-isopropoxy-4-methoxybenzoate
• Synonyms: isopropyl 2-isopropoxy-4-methoxybenzoate
• CAS NO: 1353891-99-2
• Molecular Weight: 252.31
• Mol File: 1353891-99-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: isopropyl 2-isopropoxy-4-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: isopropyl 2-isopropoxy-4-methoxybenzoate(1353891-99-2)
• EPA Substance Registry System: isopropyl 2-isopropoxy-4-methoxybenzoate(1353891-99-2)

Safety Data

• Hazardous Substances Data: 1353891-99-2(Hazardous Substances Data)

Upstream product

• 75-29-6 isopropyl chloride 
• 2237-36-7 4-methoxysalicylic acid 
• 75-26-3 isopropyl bromide 

Downstream Products

• 548472-68-0 nutlin-3a 
• 1353891-90-3 tert-butyl (1R,2S)-1,2-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxybenzamido)ethylcarbamate 
• 1353891-93-6 N-((1R,2S)-1,2-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxybenzamido)ethyl)-3-oxopiperazine-1-carboxamide 

Relevant articles and documents

The hydrophobically-tagged MDM2-p53 interaction inhibitor Nutlin-3a-HT is more potent against tumor cells than Nutlin-3a

We present the first application of hydrophobic tagging to a non-covalent inhibitor of protein-protein interactions. Nutlin-3a-HT, created by fusing the hydrophobic tag HyT13 to the MDM2-p53 interaction inhibitor Nutlin-3a, prevented cellular accumulation of MDM2 upon p53 reactivation, and had a stronger effect on cell viability and the induction of apoptosis than Nutlin-3a.

STEREOSELECTIVE METHODS, CATALYSTS AND INTERMEDIATES FOR THE SYNTHESIS OF (-)-NUTLIN-3 AND RELATED COMPOUNDS

The present invention provides methods and intermediates are provided for the preparation of (?)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use