135410-20-7 Usage
Description
Acetamiprid, also known as the (E)-stereoisomer of acetamiprid, is a pale yellow solid that belongs to the neonicotinoid class of insecticides. It is chemically related to nicotine and is known for its broad-spectrum insecticidal properties. Acetamiprid has a unique mode of action and is effective against pests that can develop resistance to other types of pesticides, such as organophosphorus, carbamates, and pyrethroids.
Uses
Used in Agricultural Industry:
Acetamiprid is used as a systemic insecticide for soil and foliar application, providing effective control of Hemiptera (especially aphids), Thysanoptera, and Lepidoptera on a wide range of crops, including vegetables, fruits, and tea.
1. Control of cucumber aphids: Acetamiprid is used as an insecticide during the full incidence beginning period of cucumber aphids. A 3% solution of Acetamiprid, mixed with 50-60 kg of water, can be uniformly sprayed to achieve good results. The efficacy of this treatment can last for more than fifty days, even in wet years.
2. Control of apple aphids: Acetamiprid is used as an insecticide during the apple tree growing period and the full incidence beginning period of aphids. A 3% solution of Mospilan, diluted 2000-2500 times, can be sprayed to effectively control aphids and provide good resistance to rain erosion. The efficacy of this treatment can last for more than twenty days.
3. Control of citrus aphids: Acetamiprid is used as an insecticide during the full incidence beginning period of aphids on citrus plants. A 3% solution of Mospilan, diluted 2000-2500 times, can be sprayed to achieve a good and persistent effect on citrus plants. It is safe for citrus plants and does not exhibit phytotoxicity under normal use.
Additionally, Acetamiprid is used to control fleas on domestic animals, as well as to control sucking and chewing insects, and soil insects such as beetles, fruit moths, leafhoppers, and miners, thrips, and whiteflies on corn and soybean seeds.
The new pesticide
Acetamiprid, also known as mospilan, is a new kind of pesticides. It is nitro methylene heterocyclic compounds. It can act on nicotinic acetylcholine receptor of the insect nervous system synapses, interfere the insect nervous system stimulation conduction, cause neurological pathways obstruction, and result in the accumulation of the neurotransmitter acetylcholine in the synapse. Then it can result in the paralysis of insect and eventually death. Acetamiprid has tag and stomach toxicity effect. Meanwhile it has a strong penetration, readily availability, and long duration.
Acetamiprid can be used for the prevention and control of aphids, planthoppers, thrips, lepidopteron and other pests on the rice, vegetables, fruit, tea bushes. At the concentration of 50 to 100 mg/L, acetamiprid can effectively control aphid, vegetables aphid, peach borer and it can kill eggs.
Physicochemical property
The original drug acetamiprid is white crystalline. Its content is more than 99%, melting point is 101～103.3℃, and vapor pressure is less than 0.33×10-6Pa (25℃). Acetamiprid is slightly soluble in water, and its solubility in the water is 4.2g/L. Acetamiprid is also soluble in acetone, methanol, ethanol, dichloromethane, chloroform, acetonitrile and the like. It is stable in the neutral or slightly acidic medium, and it can be stored at room temperature for 2 years. It can gradually hydrolyze when pH is 9 at 45℃. It is stable in sunlight.
The above information is edited by the lookchem Ge Qian.
Toxicity
According to our pesticide toxicity grading standards, acetamiprid is moderately toxic pesticides. Acute oral LD50 of rat is 146~217mg/kg weight. It has no irritation on the skin and eye. It has no mutagenic effect according to the animal tests. Acetamiprid has low toxicity to human and animal, small lethality to predators, low toxicity to fish and little effect on bees. Acetamiprid can be used to control homopteran pests of fruit trees and vegetables. It can be used to control soil insect when using granules as soil.
Considerations
1. If there are mulberry fields nearby, acetamiprid should not be sprayed on mulberry leaves because this agent is toxic for the silkworm.
2. Acetamiprid can’t be mixed with strong base agents (bordeaux mixture, lime sulfur, etc.).
3. The toxicity of acetamiprid to human and animal is low. But if it is drinked, one should be taken to the hospital to be given gastric lavage immediately and keep quiet.
Metabolic pathway
Acetamiprid is relatively stable to hydrolysis and to photodegradation
by sunlight. It is rapidly degraded in soils to form 6-chloropyridinyldimethylamine
and 6-chloronicotinic acid. The main pathways
of metabolism in plants are N-demethylation and subsequent oxidation
affording 6-chloronicotinic acid and 6-chloropicolyl alcohol. Two N-cyanoamidines
were formed after application of acetamiprid to cabbage
leaves. No information is available on the fate of the insecticide in insects
or mammals.
Degradation
Acetamiprid is stable in buffer solutions at pH 4, 5 and 7 and under
sunlight. It is degraded slowly at pH 9 (45 °C) (PM). In a study of its
hydrolysis acetamiprid was converted quantitatively to N-methyl-
(6-chloro-3-pyridyl)methylamine (2) in 0.5-1 N sodium hydroxide at
90-95°C in 2 hours (see Scheme 1). N-Demethyl-acetamiprid (3) was
converted to (6-chloro-3-pyridyl)methylamine(4) at the same rate and
under similar conditions (Tokieda et al., 1997).
Check Digit Verification of cas no
The CAS Registry Mumber 135410-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,1 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135410-20:
(8*1)+(7*3)+(6*5)+(5*4)+(4*1)+(3*0)+(2*2)+(1*0)=87
87 % 10 = 7
So 135410-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3
135410-20-7Relevant articles and documents
NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND
-
, (2017/08/26)
An object of the present invention is to provide a compound having the controlling activity on a noxious arthropod, and a noxious arthropod controlling agent containing an amide compound of formula (I): wherein X represents a nitrogen atom or a CH group, p represents 0 or 1, A represents a tetrahydrofuranyl group or the like, R1, R2, R3, R4, R5, R6 and R7 represent a hydrogen atom or the like, n represents 1 or 2, Y represents an oxygen atom or the like, m represents any integer of 0 to 7, and Q represents a C1-8 chain hydrocarbon group optionally having a phenyl group or the like, has the excellent noxious arthropod controlling effect.
Active agent combinations
-
, (2008/06/13)
The novel active compound combinations of extracts from seeds of the neem tree and the active compounds of groups (B) to (F) listed in the description have very good insecticidal and acaricidal properties.
Protection of trees
-
, (2008/06/13)
A method for the protection of trees of the families Musaceae or Plantanginaceae from destructive pests whereby the trees to be protected share a common root system.
